New scan could shine a light on hidden inflammation
NCT ID NCT07535554
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new radioactive tracer called [18F]AlF-FAPI-74 for PET/CT scans to see if it can find inflammation better than the current standard tracer. The trial will involve 140 people with fever of unknown origin, IgG4-related disease, or axial spondylarthritis. Researchers will compare the new tracer's ability to pinpoint inflammation and help make a diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- [18F]AlF-FAPI-74 (a radioactive tracer for PET/CT scans)
- What this could lead to
- If successful, this could provide a more accurate way to diagnose inflammatory diseases, potentially reducing the need for invasive biopsies and guiding treatment more effectively.
- What could go wrong
- This is a mid-stage study with only 140 participants, so results may not apply to everyone. The new tracer may not prove superior to the current standard, and its availability could be limited.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital Leuven
RECRUITINGLeuven, 3000, Belgium
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Scientists investigate immune cell role in rare IgG4 disease
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- Study on unexplained fevers in elderly withdrawn before starting
- New study: can upadacitinib ease back pain in axial spondylarthritis?