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New combo therapy aims to tame rare inflammatory disease

NCT ID NCT07068165

First seen Jan 11, 2026 · Last updated Jun 13, 2026 · Updated 22 times

Summary

This study tests whether adding lenalidomide to standard prednisone treatment can better control active IgG4-related disease, a rare condition causing swelling and damage in organs. About 198 adults will receive either low-dose lenalidomide plus prednisone, higher-dose lenalidomide plus prednisone, or prednisone alone for 52 weeks. The main goal is to see which group has fewer disease flare-ups.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Peking Union Medical College Hospital, Beijing, Beijing 100050

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Immunoglobulin G4-Related Disease immunoglobulin G4-related sclerosing disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.