IgG4 related disease
Clinical trials for IgG4 related disease explained in plain language.
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Can inhaled cell vesicles soothe damaged lungs in autoimmune disease?
Disease control Not yet recruitingThis early-phase trial tests a nebulized therapy called UC-EVs, derived from human umbilical cord cells, in adults with immune-mediated inflammatory diseases (such as IgG4-related disease or systemic sclerosis) that affect the lungs. Participants inhale the vesicles daily for 7 d…
Matched conditions: IGG4 RELATED DISEASE
Early phase 1 • Sponsor: Qiubai Li • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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Can engineered immune cells tame a stubborn autoimmune disease?
Disease control Not yet recruitingThis trial tests a single infusion of BCT301, a cell therapy made from stem cells that are engineered to target the immune system, in 6 adults with IgG4-related disease that has not improved with standard treatment. The main goal is to check whether the infusion is safe and toler…
Matched conditions: IGG4 RELATED DISEASE
Sponsor: Peking University Third Hospital • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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New drug aims to stop IgG4 disease relapses without Long-Term steroids
Disease control Not yet recruitingThis study tests a drug called IMM0306 in 125 people with IgG4-related disease, a condition where the immune system attacks organs causing swelling and damage. The goal is to see if IMM0306 can prevent disease flare-ups and allow patients to safely stop taking steroids. Participa…
Matched conditions: IGG4 RELATED DISEASE
Phase 2/3 • Sponsor: ImmuneOnco Biopharmaceuticals (Shanghai) Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Experimental CAR-T injection aims to tame autoimmune diseases
Disease control Not yet recruitingThis early-phase trial tests an injection called KSVCBD, a type of CAR-T cell therapy, in 60 adults with severe autoimmune diseases like lupus and scleroderma. The goal is to see if it's safe and to get a first look at whether it might help control the disease. Participants recei…
Matched conditions: IGG4 RELATED DISEASE
Early phase 1 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Engineered immune cells take on rare autoimmune disease
Disease control Not yet recruitingThis early-phase study tests a new treatment called KN5601, which uses specially engineered natural killer (NK) cells to target and destroy disease-causing immune cells in people with relapsed or refractory IgG4-related disease. The trial will enroll 18 adults and primarily check…
Matched conditions: IGG4 RELATED DISEASE
Early phase 1 • Sponsor: Changhai Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC