IGG4 RELATED DISEASE
Clinical trials for IGG4 RELATED DISEASE explained in plain language.
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New drug may shrink swollen glands in rare disease
Disease control Recruiting nowThis study tests a drug called efgartigimod in 5 adults with IgG4-related disease, a condition that causes swelling in glands and organs. Participants receive weekly injections for 12 weeks. The goal is to see if the drug reduces swelling in the tear glands, saliva glands, or pan…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2 • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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Could a single pill tame three rare immune diseases?
Disease control Recruiting nowThis study tests a drug that blocks a key immune signal (JAK1) in people with Behçet's disease, myositis, or IgG4-related disease. The goal is to see if it can control disease activity and reduce the need for long-term steroids. About 60 adults will take the drug and be monitored…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2 • Sponsor: UMC Utrecht • Aim: Disease control
Last updated Jun 15, 2026 19:07 UTC
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New combo therapy aims to tame rare inflammatory disease
Disease control Recruiting nowThis study tests whether adding lenalidomide to standard prednisone treatment can better control active IgG4-related disease, a rare condition causing swelling and damage in organs. About 198 adults will receive either low-dose lenalidomide plus prednisone, higher-dose lenalidomi…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New pill could tame rare inflammatory disease flares
Disease control Recruiting nowThis study tests an experimental drug called rilzabrutinib against a placebo in 124 adults with active IgG4-related disease, a rare condition causing swelling and damage in organs. The goal is to see if the drug can prevent disease flares and reduce the need for steroids over 52 …
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE3 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 09, 2026 12:08 UTC
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Engineered immune cells take on stubborn autoimmune disease
Disease control Recruiting nowThis study tests a new treatment called anti-BCMA-CD19 CAR-T cells for people with IgG4-related disease that hasn't improved with standard therapies. Nine adults will have their immune cells collected, modified, and infused back after mild chemotherapy. Researchers will monitor s…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated Jun 05, 2026 12:09 UTC
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New cell therapy trial aims to tame rare autoimmune disease
Disease control Recruiting nowThis early-stage trial tests a cell therapy called ACE1831 in 30 adults with active IgG4-Related Disease, a rare autoimmune condition that causes swelling and organ damage. The treatment uses immune cells from healthy donors to try to control the disease. The main goals are to ch…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Acepodia Biotech, Inc. • Aim: Disease control
Last updated Jun 03, 2026 12:02 UTC
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New PET scan tracer could outshine current standard for Hard-to-Diagnose inflammation
Diagnosis Recruiting nowThis study compares a new imaging tracer, [18F]-AlF-FAPI-74, with the standard [18F]-FDG in PET/CT scans for three inflammatory conditions: fever of unknown origin, IgG4-related disease, and axial spondyloarthritis. Researchers aim to see if the new tracer is as good or better at…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Diagnosis
Last updated Jun 01, 2026 18:05 UTC