Immune cell therapy shows promise for Hard-to-Treat IgG4 disease

NCT ID NCT07148791

First seen Sep 30, 2025 · Last updated May 12, 2026 · Updated 29 times

Summary

This study tests a new treatment called anti-BCMA-CD19 CAR-T cells for adults with IgG4-related disease that hasn't improved with standard therapies. Participants will have their immune cells collected, receive a short course of chemotherapy, and then get an infusion of the modified cells. The goal is to see if this therapy is safe and can reduce disease activity over 26 weeks.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Rheumatology and Immunology, the First Medical Center, Chinese PLA General Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100853, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.