B-cell mediated autoimmune disorders
Clinical trials for B-cell mediated autoimmune disorders explained in plain language.
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Could a single infusion of modified immune cells tame autoimmune attacks?
Disease control Recruiting nowThis early study tests a new treatment called azercabtagene zapreleucel (azer-cel) for people with B-cell mediated autoimmune disorders like multiple sclerosis and neuromyelitis optica. The treatment uses a patient's own immune cells that are modified in a lab to target and destr…
Matched conditions: B-CELL MEDIATED AUTOIMMUNE DISORDERS
Phase 1 • Sponsor: TG Therapeutics, Inc. • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Experimental CAR-T therapy targets stubborn autoimmune disease
Disease control Recruiting nowThis Phase 2 trial tests a personalized cell therapy called anti-BCMA-CD19 CAR-T cells in 9 adults with IgG4-related disease that hasn't responded to standard treatments. Participants receive an infusion of their own modified immune cells after a short course of chemotherapy. The…
Matched conditions: B-CELL MEDIATED AUTOIMMUNE DISORDERS
Phase 2 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated Jun 26, 2026 12:38 UTC