ICU

Researchers are testing whether cardiomyopeptidin, an intravenous drug, can protect the heart muscle of ICU patients who have signs of cardiac injury but no diagnosed heart disease. The trial enrolls 234 adults with high troponin levels during their ICU stay. Participants receive…

This trial compares three painkillers, hydromorphone, fentanyl, and butorphanol, given intravenously to ICU patients who are not on mechanical ventilation. The goal is to find the best dose of hydromorphone that achieves effective pain control while monitoring side effects like l…

This study looks at 377 adults with severe lung failure (ARDS) who were treated with prone positioning (lying face down to help breathing). Researchers will use computer models to predict which patients are at highest risk of dying in the ICU. The goal is to help doctors make bet…

This study looks at whether a fast, automatic eye test can predict delirium (sudden confusion) in intensive care patients who need a breathing machine. Delirium is common and serious, but current screening methods take time and training. Researchers will measure pupil reactions i…

This study tested whether giving a gas sedative (isoflurane) instead of standard IV drugs could reduce the energy delivered to the lungs by the breathing machine in 40 ICU patients. The goal was to see if this approach might lower the risk of lung injury. The trial was small and …

This study reviewed records from 542 adults in 20 ICUs across China who had severe flu (Influenza A) and breathing failure. Researchers divided patients into those who also developed a fungal lung infection (aspergillosis) and those who did not, to understand risk factors and sur…

This pilot study tested whether AI-generated daily written summaries can help ICU clinicians communicate better with families. Clinicians edited the AI summaries before giving them to families. The study involved 27 participants and measured how acceptable and feasible this appro…

This completed study from Ankara University looked at 146 severe COVID-19 patients in the ICU. Researchers measured red blood cell distribution width (RDW), a marker of variation in red blood cell size, to see if it could predict whether patients would need a breathing tube or di…