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Blood cell size may reveal COVID-19 severity in ICU patients

NCT ID NCT07244731

Knowledge-focused Sponsor: Ankara University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study from Ankara University looked at 146 severe COVID-19 patients in the ICU. Researchers measured red blood cell distribution width (RDW), a marker of variation in red blood cell size, to see if it could predict whether patients would need a breathing tube or die. The goal was to find a simple, inexpensive tool to help doctors make better decisions in the ICU.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors use a simple blood test to predict which COVID-19 patients in the ICU are at higher risk of death or needing a breathing tube.
What could go wrong
This is an observational study, not a treatment trial. It only shows a possible link, not cause and effect. The results may not apply to all COVID-19 patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

146 people

The number who actually took part.

Started

Sep 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Ministry of Health of the Republic of Turkey Ankara University Ibn-i-Sina Hospital Anaesthesiology and Resuscitation Department Patients admitted to the COVID-19 intensive care unit

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 years and older * Severe and critically ill COVID-19 patients (PCR test positivity of COVID) * Patients who have been monitored in the intensive care unit for at least 3 days * Patients without haematological malignancies Exclusion Criteria: * Patients under 18 years of age * Those with haematological malignancies (as this may affect RDW levels) * Patients who died within 3 days of admission to intensive care

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID -19 ICU Prognosis

Contacts and locations

Locations

  • Ankara University

    Ankara, Ankara, 06340, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.