HYPOXIC ISCHEMIC ENCEPHALOPATHY
Clinical trials for HYPOXIC ISCHEMIC ENCEPHALOPATHY explained in plain language.
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Sleep hormone could shield Babies' brains from birth injury
Disease control Recruiting nowThis study is testing whether melatonin, a natural hormone, can help protect the brains of newborns who experience oxygen deprivation during birth. Researchers are giving melatonin alongside standard cooling therapy to 70 babies to find the safest and most effective dose. The goa…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Phase: EARLY_PHASE1 • Sponsor: University of Florida • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New hope for babies with Birth-Related brain damage
Disease control Recruiting nowThis study is testing whether a new drug called sovateltide can help newborns who have brain injury from not getting enough oxygen during or around birth. The drug aims to protect brain cells and promote repair. Researchers will compare sovateltide to a placebo in 40 babies to se…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Phase: PHASE2 • Sponsor: Pharmazz, Inc. • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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Race against time: new drug trial aims to save newborn brains
Disease control Recruiting nowThis study is testing a new drug called RLS-0071 to see if it is safe and can help newborns who have brain damage from a lack of oxygen during birth. The drug is given alongside standard cooling therapy. Researchers will follow the babies for two years to check for safety and see…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Phase: PHASE2 • Sponsor: ReAlta Life Sciences, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Caffeine tested to protect newborn brains after oxygen loss
Disease control Recruiting nowThis study aims to find the best caffeine dose for newborns who experienced oxygen deprivation at birth, which can cause brain injury. Researchers will test caffeine in 16 infants who are already receiving cooling therapy to protect their brains. The main goal is to determine saf…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Phase: PHASE1 • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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Higher doses tested to halt dangerous seizures in newborn babies
Disease control Recruiting nowThis study aims to find the safest and most effective dose of the drug levetiracetam to control seizures in newborn babies. Researchers will test increasingly higher doses in up to 133 newborns who have mild to moderate seizures, comparing them to a standard treatment. The goal i…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC
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Mapping genes to unlock the mystery of newborn brain injury
Diagnosis Recruiting nowThis study aims to understand if genetic conditions play a role in a serious newborn brain injury called HIE. Researchers will offer detailed genetic testing (genome sequencing) to 25 newborns with HIE who are receiving cooling therapy and their parents. The goal is to see how of…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Diagnosis
Last updated Apr 03, 2026 18:10 UTC
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Two-Week therapy blitz aims to boost Kids' brain function
Symptom relief Recruiting nowThis study is observing whether a short, intensive therapy program helps children with various brain development disorders. About 100 children, aged 4 to 12 with conditions like cerebral palsy or autism, will receive personalized therapy for 2.5 hours a day over two weeks. Resear…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Sponsor: Healing Hope International • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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Brain scans could predict who wakes up from coma
Knowledge-focused Recruiting nowThis study aims to identify which factors best predict whether patients with severe brain injuries will regain consciousness during rehabilitation. Researchers will observe 130 patients in a coma or similar state, tracking their brain scans, electrical activity, and health status…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Sponsor: BDH-Klinik Hessisch Oldendorf • Aim: Knowledge-focused
Last updated Mar 04, 2026 15:30 UTC