HYPOTENSION

This study compares two drugs, norepinephrine and phenylephrine, given as a steady drip during C-sections to keep blood pressure stable. It includes 140 healthy pregnant women having planned C-sections. The goal is to see which drug leads to better outcomes for both mother and ba…

This study tests whether giving a drug called noradrenaline during non-cardiac surgery can prevent episodes of very low blood pressure better than standard care. About 750 adults aged 45 and older having surgery lasting at least one hour will take part. The goal is to see if this…

This study looks at how to best give hydrocortisone (a steroid) to newborns who have low blood pressure while being cooled for birth asphyxia. About 50 full-term babies will receive the drug, and researchers will measure how their bodies process it. The goal is to find the right …

This study tests whether a short, guided breathing exercise done right before spinal anesthesia can help prevent a dangerous drop in blood pressure during planned C-sections. About 150 pregnant women will be randomly assigned to either do the breathing exercise or receive standar…

This study tests a non-invasive spinal stimulation technique to help control blood pressure in people who had a spinal cord injury within the past month. Many of these individuals experience dangerous drops in blood pressure when sitting up, causing dizziness and nausea that can …

This study compares two types of ultrasound-guided nerve blocks (S-FICB and PENG) to see which one better reduces pain when patients with a broken femur need to sit up for spinal anesthesia. About 70 adults aged 20-70 will take part. The goal is to make positioning less painful a…

This study compares two drugs, dexmedetomidine and dexamethasone, added to a standard numbing medicine (ropivacaine) for arm surgery. The goal is to see which one helps the numbness start faster and last longer. About 66 adults having upper arm surgery will take part. The results…

This study tests whether gentle electrical stimulation on the back can help people with chronic spinal cord injury maintain healthy blood pressure when they sit up. Participants will lie on a tilt table while their blood pressure is measured with and without stimulation. The goal…

This study looks at 206 people having surgery to remove a pancreatic tumor. It compares standard anesthesia to a combination of general anesthesia and an epidural to see which method causes fewer drops in blood pressure during the operation. The goal is to find the safer approach…

This study looks at whether measuring skin conductance, a sign of nerve activity, can predict sudden drops in blood pressure after spinal anesthesia in older cancer patients. About 100 people aged 65 and older having urologic cancer surgery will be monitored. The goal is to find …

This study checks if a woman's waist size, body mass index (BMI), and a heart-related index can predict a common complication of spinal anesthesia during C-sections: a sudden drop in blood pressure. Researchers will measure 321 pregnant women before their scheduled C-section and …

This study aims to find out which of two common blood pressure drugs, noradrenaline or phenylephrine, is better at keeping blood flowing to the brain and other organs during brain surgery. Researchers will measure blood flow and oxygen use in the brain using a special scan. The s…

This study looks at how well different tests can predict whether a patient with low blood pressure and impaired consciousness will benefit from receiving extra fluids. The researchers will compare several methods, including leg raising and fluid challenges, in 222 adults in inten…

This study looks at how four different blood pressure medicines (ephedrine, phenylephrine, norepinephrine, and vasopressin) affect the contraction of uterine muscle and umbilical cord blood vessels. Researchers will test these drugs on tissue samples from 144 women having planned…