HYPOSPADIAS
Clinical trials for HYPOSPADIAS explained in plain language.
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New study tests extra tissue flap to improve hypospadias surgery outcomes
Disease control CompletedThis study looked at 120 boys aged 2-12 with a common birth defect where the urinary opening is on the underside of the penis (distal hypospadias). Researchers compared two surgical repair methods: one using a standard double-layer tissue cover, and another adding an extra tissue…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Javaid Afridi • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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Second-Time fix for birth defect shows promise in small study
Disease control CompletedThis study tested a single-stage surgery for children who needed a second hypospadias repair. It included 15 children whose urethral plate was healthy enough for the procedure. The goal was to see how successful the surgery was and to track complications like fistulas or narrowin…
Matched conditions: HYPOSPADIAS
Sponsor: Tanta University • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Pee power: urine stem cells may fix penile defects in kids
Disease control CompletedThis study tested a new approach to reduce complications in boys born with hypospadias, a condition where the urinary opening is on the underside of the penis. Researchers used exosomes (tiny healing particles) from the boys' own urine stem cells during surgery to help rebuild th…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Shanghai Children's Hospital • Aim: Disease control
Last updated May 18, 2026 12:06 UTC
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Estrogen cream may help boys with birth defect heal better after surgery
Symptom relief CompletedThis study tested whether applying estrogen cream to the penis for two months before surgery could reduce healing problems in 244 boys with severe hypospadias, a birth defect where the urethra doesn't form properly. The goal was to see if it lowers the risk of post-surgery compli…
Matched conditions: HYPOSPADIAS
Phase: PHASE3 • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated May 26, 2026 10:29 UTC
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New study finds better way to ease pain after Kids' surgery
Symptom relief CompletedThis study tested two types of nerve blocks to see which one works better for pain relief after hypospadias surgery in children aged 1 to 6. Sixty children received either a pudendal nerve block or a dorsal penile nerve block guided by ultrasound. Researchers measured pain levels…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Bangladesh Medical University • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Which pain block works best for little Boys' surgery?
Symptom relief CompletedThis study looked at 86 children aged 1 to 7 having hypospadias repair. Researchers compared two types of pain blocks given during surgery: a sacral erector spinae plane block and a caudal epidural block. They measured pain levels using a special scale at several times over the f…
Matched conditions: HYPOSPADIAS
Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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New pain block study aims to improve comfort for young surgery patients
Symptom relief CompletedThis study tested two different ultrasound-guided pain blocks for children aged 1-7 having hypospadias surgery. The goal was to see which block provides longer pain relief after surgery. Thirty children participated, and researchers measured how soon they needed extra pain medici…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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Scientists hunt for hidden genes behind common birth defect
Knowledge-focused CompletedThis study looked at the DNA of 60 people with a family history of hypospadias, a condition where the opening of the urethra is not at the tip of the penis. The goal was to find new genetic changes that might cause the condition. By comparing genomes of affected family members, r…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 26, 2026 10:27 UTC
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Study asks: is a stent needed after penile surgery in boys?
Knowledge-focused CompletedThis study looked at 110 boys aged 1–12 having surgery for hypospadias, a birth condition where the urine opening is on the underside of the penis. Half received a temporary stent (small tube) after surgery, and half did not. The goal was to see which approach leads to fewer leak…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Children's Hospital and Institute of Child Health, Multan • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Study seeks best urine drainage method after penis surgery
Knowledge-focused CompletedThis study looked at 86 boys who had surgery to fix a common birth defect where the urine opening is on the underside of the penis (distal hypospadias). The goal was to find the best way to drain urine after surgery to prevent complications like fistulas (abnormal openings). Rese…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Researchers compare penile measurements in boys with and without hypospadias
Knowledge-focused CompletedThis study measured the size of the penis and glans (tip) in 410 boys undergoing urologic surgery, comparing those with hypospadias to those without. The goal was to understand normal growth patterns by age, weight, and ethnicity. No treatment was given—only measurements were tak…
Matched conditions: HYPOSPADIAS
Sponsor: Albany Medical College • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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10 men revisited years after childhood penile surgery
Knowledge-focused CompletedThis study looked at 10 males who had surgery for hypospadias (a birth defect where the urine opening is not at the tip of the penis) during childhood. The goal was to see how they were doing after puberty, checking for complications, urinary symptoms, and sexual function. Resear…
Matched conditions: HYPOSPADIAS
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC