Hypoparathyroidism
Clinical trials for Hypoparathyroidism explained in plain language.
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A gland transplant that could end a lifetime of calcium shots?
Cure CancelledThis trial tests whether transplanting parathyroid glands from a donor can help people with severe hypoparathyroidism—a condition where the body can't regulate calcium, often after neck surgery. Participants are adults aged 18-80 who have had the condition for at least a year and…
Matched conditions: HYPOPARATHYROIDISM
Sponsor: University of Alabama at Birmingham • Aim: Cure
Last updated Aug 23, 2026 00:00 UTC
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MRNA therapy takes on hormone deficiency
Disease control PausedThis early-phase trial tests an mRNA drug called XH02 in 6 adults with hypoparathyroidism, a condition where the body lacks parathyroid hormone (PTH). The drug is designed to instruct cells to produce PTH after being given through a vein. The main goal is to check safety, while a…
Matched conditions: HYPOPARATHYROIDISM
Early phase 1 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Sep 21, 2026 14:00 UTC
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New calcium pill could ease burden for hypoparathyroidism patients
Disease control OngoingThis study tests a new form of calcium called AMOR-1 in 81 adults with hypoparathyroidism, a condition where the body can't control calcium levels. Participants will take either AMOR-1 or standard calcium pills to see if AMOR-1 can better maintain normal calcium levels while allo…
Matched conditions: HYPOPARATHYROIDISM
Phase 2 • Sponsor: Amorphical Ltd. • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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New Once-Weekly shot shows promise for Long-Term hypoparathyroidism control
Disease control OngoingThis study looks at the long-term safety of an experimental drug called MBX 2109 for people with hypoparathyroidism, a condition where the body doesn't produce enough parathyroid hormone. About 60 adults who finished a 12-week phase 2 study will receive weekly injections of MBX 2…
Matched conditions: HYPOPARATHYROIDISM
Phase 2 • Sponsor: MBX Biosciences • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC