HYPOPARATHYROIDISM
Clinical trials for HYPOPARATHYROIDISM explained in plain language.
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MRNA injection could replace missing hormone in rare disease
Disease control Recruiting nowThis early-stage trial tests an mRNA drug called XH-02 in 15 adults with hypoparathyroidism, a condition where the body doesn't make enough parathyroid hormone. The drug is injected under the skin to help the body produce the missing hormone. The main goal is to check safety, but…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE1, PHASE2 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New pill could cut calcium pills for rare hormone disorder
Disease control Recruiting nowThis study tests a new drug called AMOR-1 for adults with hypoparathyroidism, a condition where the body can't control calcium levels. The goal is to see if AMOR-1 can safely reduce the need for daily calcium supplements while keeping blood calcium in a healthy range. About 81 pa…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE2 • Sponsor: Amorphical Ltd. • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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MRNA therapy offers hope for rare hormone disorder
Disease control Recruiting nowThis study tests an mRNA drug called XH-02 that helps the body produce a missing hormone (PTH) in adults with hypoparathyroidism. The drug is given as a shot under the skin. The goal is to see if it is safe and can better control calcium and phosphorus levels than standard treatm…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE2 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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MRNA therapy takes on rare hormone disorder
Disease control Recruiting nowThis early-stage trial tests an experimental mRNA drug called XH02 in 6 adults with hypoparathyroidism, a condition where the body lacks parathyroid hormone (PTH). The drug aims to temporarily replace PTH after a single intravenous dose. Researchers will monitor safety and measur…
Matched conditions: HYPOPARATHYROIDISM
Phase: EARLY_PHASE1 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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Parathyroid transplant trial offers hope for rare hormone disorder
Disease control Recruiting nowThis early-phase study tests whether transplanting donated parathyroid tissue into the forearm can help people with hypoparathyroidism achieve normal calcium and phosphorus levels. The trial enrolls 3 adults who have had low parathyroid hormone for at least a year. Participants w…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE1, PHASE2 • Sponsor: Peter Stock • Aim: Disease control
Last updated May 11, 2026 20:53 UTC
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New hope for hypoparathyroidism: Higher-Dose drug trial launches
Disease control Recruiting nowThis study tests a daily injection of palopegteriparatide at higher doses in adults with hypoparathyroidism, a condition where the body doesn't produce enough parathyroid hormone. The goal is to see if the drug can safely keep calcium levels normal while reducing the need for vit…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE3 • Sponsor: Ascendis Pharma Bone Diseases A/S • Aim: Disease control
Last updated May 08, 2026 12:02 UTC
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New study checks drug levels in breast milk for moms on YORVIPATH
Knowledge-focused Recruiting nowThis study looks at how much of the drug palopegteriparatide (YORVIPATH) passes into breast milk. It involves 10 lactating women with hypoparathyroidism who are already taking the drug and choose to breastfeed. Researchers will collect milk samples to measure drug levels, helping…
Matched conditions: HYPOPARATHYROIDISM
Sponsor: Ascendis Pharma A/S • Aim: Knowledge-focused
Last updated May 17, 2026 02:05 UTC
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Researchers watch Hypoparathyroidism's Long-Term effects on kidneys and brain
Knowledge-focused Recruiting nowThis study follows 106 adults with hypoparathyroidism for three years to see how the disease damages organs like the kidneys and brain. Participants get regular blood tests and optional CT scans. The goal is to better understand the disease, not to test a new treatment.
Matched conditions: HYPOPARATHYROIDISM
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Behind the scenes: scientists Double-Check lab tests for better research
Knowledge-focused Recruiting nowThis study aims to validate and check the reproducibility of laboratory tests, equipment, and techniques used in research on chronic diseases like obesity, diabetes, and heart disease. Researchers will compare old and new testing methods to ensure results are accurate and consist…
Matched conditions: HYPOPARATHYROIDISM
Sponsor: Bettina Mittendorfer • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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New registry to monitor YORVIPATH's effects on pregnant women and babies
Knowledge-focused Recruiting nowThis study is a pregnancy registry that collects information from women aged 15 to 50 who took YORVIPATH for hypoparathyroidism around the time of conception or during pregnancy. Researchers will track pregnancy complications, birth outcomes, and infant health for at least one ye…
Matched conditions: HYPOPARATHYROIDISM
Sponsor: Ascendis Pharma A/S • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC