HYPOPARATHYROIDISM
Clinical trials for HYPOPARATHYROIDISM explained in plain language.
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New hope for rare hormone disorder: drug may cut pill burden
Disease control CompletedThis study tested a new drug, palopegteriparatide, in 90 adults with chronic hypoparathyroidism, a condition where the body lacks parathyroid hormone. The goal was to see if the drug could help patients stop taking daily vitamin D and calcium supplements. Results showed many pati…
Matched conditions: HYPOPARATHYROIDISM
Sponsor: National and Kapodistrian University of Athens • Aim: Disease control
Last updated May 17, 2026 08:16 UTC
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New daily shot could free patients from calcium pills and vitamin d
Disease control CompletedThis study tested a daily injection called TransCon PTH in 81 adults with hypoparathyroidism, a condition where the body lacks parathyroid hormone, causing low calcium levels. The goal was to see if the drug could bring calcium levels back to normal and allow patients to stop tak…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE3 • Sponsor: Visen Pharmaceuticals (Shanghai) Co., Ltd. • Aim: Disease control
Last updated May 17, 2026 08:01 UTC
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Breakthrough injection could free patients from daily calcium pills
Disease control CompletedThis phase 3 trial tested a daily injection called TransCon PTH in 84 adults with hypoparathyroidism, a condition where the body lacks parathyroid hormone, leading to low calcium levels. Participants were randomly assigned to receive either the drug or a placebo for 26 weeks, and…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE3 • Sponsor: Ascendis Pharma Bone Diseases A/S • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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Pump delivery may improve mineral balance in hypoparathyroidism
Disease control CompletedThis study tested whether delivering parathyroid hormone (PTH 1-34) through a small pump, similar to an insulin pump, works better than standard twice-daily injections for people with chronic hypoparathyroidism. The goal was to keep blood and urine calcium levels stable throughou…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE2 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Disease control
Last updated May 07, 2026 18:43 UTC
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New weekly shot could reduce pills for rare hormone disorder
Disease control CompletedThis study tested a new medicine called MBX 2109, given as a weekly shot, in 64 adults with hypoparathyroidism. The goal was to see if it could safely help patients lower their daily calcium and vitamin D pills while keeping blood calcium levels normal. The trial was completed an…
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE2 • Sponsor: MBX Biosciences • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Simple blood test after thyroid surgery could spare patients unnecessary worry
Diagnosis CompletedThis study looked at 300 patients who had their thyroid gland removed. Doctors measured their parathyroid hormone (PTH) levels right after surgery to see if a low level could predict dangerously low calcium (hypoparathyroidism). The goal was to find a cutoff value that reliably r…
Matched conditions: HYPOPARATHYROIDISM
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 14, 2026 12:03 UTC
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Blue dye spray may prevent voice loss in thyroid surgery
Symptom relief CompletedThis study tested whether spraying a blue dye called methylene blue during thyroid surgery helps surgeons see and protect the nerve that controls the voice and the glands that manage calcium levels. 136 adults with benign thyroid nodules took part. The goal was to reduce complica…
Matched conditions: HYPOPARATHYROIDISM
Phase: NA • Sponsor: Services Hospital, Lahore • Aim: Symptom relief
Last updated May 17, 2026 08:01 UTC
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New oral tablets for bone health tested against injections
Knowledge-focused CompletedThis early-stage study tested several new oral tablet versions of a bone-building hormone (hPTH(1-34)) in 45 healthy men aged 18-35. The goal was to see how well the body absorbs these new tablets compared to an existing oral tablet and a standard injection. The study focused on …
Matched conditions: HYPOPARATHYROIDISM
Phase: PHASE1 • Sponsor: Entera Bio Ltd. • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Study checks what patients and doctors know about NATPARA risks
Knowledge-focused CompletedThis study surveyed 200 patients and doctors to see how well they understand the risks and safe use of NATPARA, a drug for hypoparathyroidism. Participants answered questions online, by phone, or on paper. No study medicine was given. The goal was to measure knowledge, not to tre…
Matched conditions: HYPOPARATHYROIDISM
Sponsor: Shire • Aim: Knowledge-focused
Last updated May 08, 2026 12:02 UTC