HYPERTENSION, PULMONARY
Clinical trials for HYPERTENSION, PULMONARY explained in plain language.
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Could a natural hormone help COPD patients breathe easier?
Disease control CompletedThis study tested whether a natural hormone called DHEA can help adults with COPD who also have high blood pressure in their lungs (pulmonary hypertension). 51 participants took either a low or high dose of DHEA daily for one year. The main goal was to see if DHEA improved how fa…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated May 26, 2026 09:31 UTC
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PAH patients get extended access to riociguat in safety study
Disease control CompletedThis study gave long-term riociguat (Adempas) to 18 adults with pulmonary arterial hypertension who had already taken the drug in earlier Bayer trials. The main goal was to check safety and side effects over time. Patients stayed on the drug until it was no longer helpful or beca…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE4 • Sponsor: Bayer • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New PAH pill aims to keep patients out of hospital
Disease control CompletedThis study tested an experimental pill called ralinepag for people with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work too hard. About 687 adults with PAH took either ralinepag or a placebo on top of their usual treatments. The goal was …
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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New drug shows promise for hard-to-treat lung-heart condition
Disease control CompletedThis study tested a drug called sotatercept in 164 adults with a specific type of pulmonary hypertension caused by heart failure. The goal was to see if it improves blood flow in the lungs and walking ability compared to a placebo. Participants received either the drug or a place…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE2 • Sponsor: Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Blood test could spot hidden lung disease before It's too late
Diagnosis CompletedThis study looked for special markers in the blood that could help doctors find pulmonary hypertension (high blood pressure in the lungs) earlier. Researchers tested blood samples from over 900 people and compared the results to a standard heart test. The goal is to create a simp…
Matched conditions: HYPERTENSION, PULMONARY
Phase: EARLY_PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Diagnosis
Last updated May 26, 2026 09:45 UTC
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Inflammation markers studied in kids with heart defects and lung hypertension
Knowledge-focused CompletedThis study looked at whether a specific inflammatory protein, HMGB1, is higher in children with congenital heart disease and pulmonary hypertension compared to those with heart disease alone or healthy children. Researchers measured blood samples from 74 children during heart cat…
Matched conditions: HYPERTENSION, PULMONARY
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC