Could a hormone supplement ease lung pressure in COPD?
NCT ID NCT00581087
First seen Jun 14, 2026 · Last updated Jun 19, 2026 · Updated 2 times
Summary
This study tested whether a daily dose of the hormone DHEA can help adults with COPD who also have high blood pressure in their lungs. Sixty participants took either DHEA or a placebo for one year. Researchers measured how far they could walk in six minutes and checked heart and lung function to see if DHEA improves exercise capacity and blood flow.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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APHP hospital Antoine Béclère GHU sud
Clamart, 92141, France
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University Hospital, Bordeaux
Bordeaux, France
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University Hospital, Limoges
Limoges, France
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University Hospital, Strasbourg
Strasbourg, France
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University Hospital, Toulouse
Toulouse, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dehydroepiandrosterone (DHEA)
What this could lead to
If it works, this could point toward a new treatment option for pulmonary hypertension in people with COPD, potentially improving exercise capacity and heart function.
What could go wrong
This is a small, completed Phase 3 trial with only 60 participants, so results may not apply to everyone. DHEA may not improve symptoms or could cause side effects like hormonal changes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.