HYPERCAPNIA

This study tests a new ventilator (INBENTUS VERSATILE) in 81 adults who need help breathing due to conditions like pneumonia, ARDS, or COPD. Participants will use the ventilator for 3 to 48 hours, and researchers will monitor for side effects and how well the machine works. The g…

This study compares a new asymmetric nasal high-flow interface to a standard nasal cannula in 50 people with mild-to-moderate COPD flare-ups. The goal is to see if the new device lowers carbon dioxide levels, reduces breathing rate, and improves comfort. Each participant will try…

This study tests whether breathing air with slightly higher carbon dioxide (hypercapnia) for two weeks can improve breathing and reduce sleep apnea in veterans with spinal cord injury. About 30 adults with chronic spinal cord injury or able-bodied people with sleep apnea will tak…

This study looks at whether changing the amount of carbon dioxide (CO2) in a child's breath during anesthesia affects how deeply asleep they are. Researchers will measure brain activity in 100 children aged 3-11 undergoing minor procedures. The goal is to see if higher CO2 levels…

This study looks at 25 people with COPD and high carbon dioxide levels who need a breathing mask (non-invasive ventilation) to help them breathe. Researchers want to see if nighttime breathing problems can predict how well the treatment works over 6 to 12 months. They will also c…

This study looks at what causes oxygen toxicity in scuba divers. Researchers want to see how things like breathing muscle training, lack of sleep, certain medications, and carbon dioxide affect risk. 62 healthy divers aged 18-45 will exercise underwater and in dry conditions to m…