HUMAN PAPILLOMA VIRUS

This study looks at whether women living with HIV can get the same protection from the HPV vaccine with 2 doses instead of the usual 3. Researchers will compare immune responses in 275 Canadian women aged 18-45 who have never received the HPV vaccine. If 2 doses work as well, it …

This study tests whether educational materials and a short video can help people who are underserved learn about the HPV vaccine and get it. The program is for Denver Health patients aged 9-26 who haven't started or finished the vaccine series. Researchers will measure changes in…

This early-phase study tests whether injecting the numbing drug lidocaine directly into HPV-related throat tumors before robotic surgery is safe and can help kill more cancer cells. About 30 adults with oropharyngeal cancer will receive either lidocaine or no injection before the…

This early-phase study tests two drugs, lenvatinib and pembrolizumab, in 20 people with HPV-related recurrent respiratory papillomatosis (RRP), a condition causing non-cancerous growths in the airway. The goal is to see if the combination shrinks lung growths and reduces the need…

This study is for people with HPV-positive throat cancer. It tests whether a much lower dose of radiation (30 Gy) combined with standard chemotherapy works as well as the usual high dose (70 Gy) to control the cancer, while causing fewer side effects. About 121 participants will …

This study explores whether women can accurately collect their own samples to test for HPV, the virus that can cause cervical cancer. Researchers will compare results from two different self-collection kits to standard Pap smears. The goal is to make screening easier and more acc…

This study aims to prevent cervical cancer by testing women for high-risk HPV and offering same-day treatment if needed. About 5,000 women in Honduras will use a self-sampling kit or have a provider-collected sample. The test gives results in under an hour, and AI imaging helps d…

This study looks at how to better prevent cervical cancer in women who have experienced homelessness, substance use, transactional sex, or incarceration. Researchers will offer HPV vaccination and testing during regular sexual health clinic visits to see if this approach works an…

This study aims to learn more about oropharyngeal carcinoma, a type of throat cancer, and its link to HPV. Researchers will collect blood samples from 1000 patients before treatment and at six follow-up visits, plus tumor tissue when available. The goal is to better understand ho…