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New drug combo targets rare HPV throat tumors

NCT ID NCT04645602

First seen Nov 15, 2025 · Last updated May 01, 2026 · Updated 17 times

Summary

This early-phase study tests two drugs, lenvatinib and pembrolizumab, in 20 people with HPV-related recurrent respiratory papillomatosis (RRP), a condition causing non-cancerous growths in the airway. The goal is to see if the combination shrinks lung growths and reduces the need for repeated surgeries. Participants must have lung involvement and be willing to undergo regular monitoring.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.