HUMAN PAPILLOMA VIRUS

This study looks at whether giving clinics financial rewards can improve how they talk about and give the HPV vaccine. About 34 clinics in North Carolina will either get communication training alone or training plus a financial incentive program. The goal is to see if these rewar…

This study tests whether adding experimental drugs HB-201 and HB-202 to standard chemotherapy can shrink HPV16-positive throat tumors more effectively. The goal is to reduce the amount of radiation and chemotherapy needed afterward, potentially lowering side effects. About 35 adu…

This study looks at whether giving lower doses of radiation to a smaller area after robotic surgery can still keep HPV-positive throat cancer from coming back. About 150 adults with early-stage cancer will receive this gentler treatment. The goal is to see if two years later the …

This study checks if a new, low-cost HPV test (ScreenFire) that women can do themselves works as well as the standard test done by a doctor. About 9,100 women aged 30-59 will take part. The goal is to see if the self-test catches high-grade cervical cancer just as accurately, and…

This study tests a program to help more HIV-positive adults get the HPV vaccine, which can prevent HPV-related cancers. People with HIV are at much higher risk for these cancers. The program gives clinics and doctors tools and training to encourage vaccination. The study will enr…

This study tests whether one dose of the HPV vaccine works as well as two or three doses in preventing cervical cancer in Tanzanian girls aged 9-14. About 900 girls will receive different numbers of doses and be followed for up to 9 years. If one dose is enough, it could make the…

This study looks at whether a single dose of the HPV vaccine can prevent HPV infection in women living with HIV who have already been vaccinated. About 778 women are taking part, and half get the vaccine right away while the others wait. Researchers will track infections and side…

This study looks at ways to help primary care clinics give more HPV vaccines to children ages 9-12. Some clinics get communication training, while others also get tools to use their existing vaccine standing orders. The goal is to see if these steps increase the number of kids wh…

This study screens 1500 adults for oral HPV infection and related antibodies to identify those at higher risk for HPV-related throat cancer. Researchers follow participants over time to see which infections persist and what factors (like mouth bacteria or immune response) play a …