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Experimental vaccine combo aims to shrink throat tumors and cut radiation dose

NCT ID NCT05108870

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 25 times

Summary

This study tests whether adding experimental drugs HB-201 and HB-202 to standard chemotherapy can shrink HPV16-positive throat tumors more effectively. The goal is to reduce the amount of radiation and chemotherapy needed afterward, potentially lowering side effects. About 35 adults with HPV16-positive oropharyngeal cancer will participate for around 2 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Chicago

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.