New combo therapy aims to shrink throat tumors and cut radiation side effects

NCT ID NCT05108870

First seen Oct 31, 2025 · Last updated May 09, 2026 · Updated 23 times

Summary

This study tests whether adding experimental immune-boosting drugs (HB-201 and HB-202) to standard chemotherapy can shrink HPV16-positive throat tumors more effectively. The goal is to reduce the amount of radiation or chemotherapy needed afterward, potentially lowering side effects. About 35 adults with HPV16+ oropharyngeal cancer will participate for roughly 2 years.

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Contacts and locations

Locations

  • University of Chicago

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.