HPV

This study was designed for people with HPV-positive oropharyngeal cancer who still have signs of the virus in their blood after finishing standard treatment. The goal was to see if an immunotherapy drug called BALSTILIMAB could clear the virus and improve long-term survival. How…

This study tests whether adding experimental drugs HB-201 and HB-202 to standard chemotherapy can shrink HPV16-positive throat tumors more effectively. The goal is to reduce the amount of radiation and chemotherapy needed afterward, potentially lowering side effects. About 35 adu…

This study tests a combination of three drugs (entinostat, PDS01ADC, and bintrafusp alfa) in adults with advanced cancers linked to HPV or certain colon cancers that haven't responded to standard treatments. The goal is to find a safe dose and see if the treatment can shrink tumo…

This study looks at whether letting women collect their own samples for HPV testing at home or in community locations can increase cervical cancer screening rates. About 1,000 women in Quebec aged 25-65 will try different ways to get and return a self-sampling kit. The goal is to…

This study tests a new community-designed campaign to help prevent HPV, a virus that can cause cancer. About 1,838 mothers and daughters in Nigeria will take part. The campaign encourages girls to get the HPV vaccine and mothers to do a simple self-test for HPV, aiming to make pr…

This study tests if offering the HPV vaccine to children at age 9-10, instead of the usual 11-12, leads to more kids getting fully vaccinated before they are exposed to the virus. The goal is to prevent HPV-related cancers later in life. About 3,100 children in Colorado and Calif…

This study tests a school-based program to help more children in South Africa get the HPV vaccine, which prevents several cancers. The program involves 600 fifth graders (ages 9-12) and their parents, working with local schools to make vaccination easier. The goal is to see if th…

This study looks at whether offering cervical cancer screening in the emergency department can help reach people who are not getting screened regularly. About 200 women and transgender/non-binary individuals with a cervix, aged 25-65, will be offered self-sampling or clinic-based…

This study will check how well the HPV vaccine works in women living with HIV and find better ways to screen for cervical cancer. About 650 women will use a self-testing kit at home, and those with positive results will get further exams. The goal is to improve health outcomes fo…

This study tracks 17 healthy adults aged 18-45 who receive the standard three-dose HPV vaccine. Researchers collect blood, saliva, lymph node, and bone marrow samples over five years to understand how the body builds and maintains strong antibody defenses. The goal is to learn wh…