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Simple blood test could spot returning throat cancer sooner

NCT ID NCT04965792

First seen Jun 22, 2026 · Last updated Jun 22, 2026

Summary

This study is testing a blood test that looks for HPV DNA in the blood of people treated for HPV-positive oropharyngeal cancer. The goal is to see if the test can find cancer recurrence earlier than standard follow-up methods. About 150 participants are being followed after treatment to compare the blood test results with routine scans and exams.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Blood test for circulating HPV DNA

What this could lead to

If successful, this blood test could help catch cancer return earlier than current methods, potentially improving treatment timing and outcomes.

What could go wrong

This is an early-stage study with 150 participants, so results may not apply to everyone. The test might miss some recurrences or give false alarms.

Conditions

The condition(s) this trial relates to.

Papillomavirus Infections Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.