HIV pre-exposure prophylaxis
Clinical trials for HIV pre-exposure prophylaxis explained in plain language.
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Monthly HIV prevention pill could replace daily dose
Prevention OngoingThis large phase 3 trial is testing whether a new oral pill called MK-8527, taken just once a month, can prevent HIV infection as well as the standard daily PrEP pill. About 4,390 people at risk of HIV will be randomly assigned to receive either the monthly pill or daily Truvada …
Matched conditions: HIV PRE-EXPOSURE PROPHYLAXIS
Phase 3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Prevention
Last updated Sep 20, 2026 00:00 UTC
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Yearly HIV prevention shot could change the game
Prevention OngoingThis study tests a new shot called lenacapavir, given once a year, to see if it can safely prevent HIV in people at risk. About 350 participants will receive the injection and be monitored for side effects and drug levels. If successful, this could offer a much more convenient op…
Matched conditions: HIV PRE-EXPOSURE PROPHYLAXIS
Phase 3 • Sponsor: Gilead Sciences • Aim: Prevention
Last updated Aug 30, 2026 00:00 UTC
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New app could bridge the gap between HIV Self-Testing and PrEP access
Prevention By invitation onlyThis study is testing a mobile-friendly app called DASH that provides information and guidance about PrEP (a daily pill that prevents HIV) to people who have used an HIV self-test kit. The app helps users explore their values and make informed decisions about starting PrEP, with …
Matched conditions: HIV PRE-EXPOSURE PROPHYLAXIS
Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 13:01 UTC
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New program aims to boost HIV prevention in black men
Prevention By invitation onlyThis study tests a personalized support program (C4) to help Black men who have sex with men take their HIV prevention medication (PrEP) consistently. About 350 men will either get the program or standard care. The program addresses personal needs like mental health and housing t…
Matched conditions: HIV PRE-EXPOSURE PROPHYLAXIS
Sponsor: University of Maryland, Baltimore • Aim: Prevention
Last updated Jun 27, 2026 12:28 UTC
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Can a phone app boost HIV prevention in rural america?
Prevention OngoingThis study tests a mobile app called Combine to help gay, bisexual, and other men who have sex with men in rural southern US get tested for HIV and STIs and start taking PrEP (a daily pill that prevents HIV). About 473 men will use the app and be placed into one of four groups: s…
Matched conditions: HIV PRE-EXPOSURE PROPHYLAXIS
Sponsor: Emory University • Aim: Prevention
Last updated Jun 27, 2026 07:55 UTC