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Can a phone app boost HIV prevention in rural america?

NCT ID NCT06205368

Prevention Sponsor: Emory University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a mobile app called Combine to help gay, bisexual, and other men who have sex with men in rural southern US get tested for HIV and STIs and start taking PrEP (a daily pill that prevents HIV). About 473 men will use the app and be placed into one of four groups: some get just the app, others can also order home test kits, some get a motivational interview, and some get both. Researchers will compare the groups to see which approach works best for increasing testing and PrEP use over 24 months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

473 people

The number who actually took part.

Started

Mar 2024

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria * Assigned male at birth and currently identifies as male * Age 18-45 years, inclusive * Reside in the U.S. South as defined by the Census Bureau or in Missouri * Reside in a county classified as rural using the Index of Relative Rurality * Have an Android or iPhone operating system (iOS) phone with active service * Willing to download a study app to their phone * English speaker * Report anal sex with a man in the past 12 months * HIV-negative or unknown serostatus * Not currently using PrEP Exclusion criteria \- Unable to provide consent

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Conditions

The condition(s) this trial relates to.

Homosexuality HIV infectious disease prevention target sexually transmitted disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV infections HIV pre-exposure prophylaxis STI

Contacts and locations

Locations

  • Emory University

    Atlanta, Georgia, 30322, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.