HIV pre-exposure prophylaxis
Clinical trials for HIV pre-exposure prophylaxis explained in plain language.
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Monthly pill could revolutionize HIV prevention
Prevention CompletedThis study tested an experimental oral drug called MK-8527, taken once a month, to see if it is safe and how it works in the body for HIV prevention. 352 HIV-negative adults at low risk for infection participated. The main goals were to check for side effects and measure drug lev…
Matched conditions: HIV PRE-EXPOSURE PROPHYLAXIS
Phase 2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Prevention
Last updated Jun 27, 2026 08:09 UTC
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Breastfeeding moms needed for HIV drug study
Knowledge-focused CompletedThis completed Phase 1 study tested how the experimental HIV prevention drug MK-8527 moves into breast milk. Thirteen healthy lactating women took a single oral dose, then provided milk and blood samples over five days. The goal was to measure how much drug reaches the baby throu…
Matched conditions: HIV PRE-EXPOSURE PROPHYLAXIS
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC