HISTIOCYTOSIS
Clinical trials for HISTIOCYTOSIS explained in plain language.
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New hope for kids with rare immune disease: trametinib trial launched
Disease control Recruiting nowThis study looks at how to best use the drug trametinib in children with histiocytosis, a rare disease where immune cells build up and cause damage. It is for kids whose disease did not respond to standard treatments or who do not have the BRAF gene change. The goal is to find th…
Matched conditions: HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Anna Raciborska • Aim: Disease control
Last updated May 26, 2026 07:14 UTC
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New pill targets hard-to-treat cancers with KRAS and BRAF mutations
Disease control Recruiting nowThis early-stage study tests an oral drug called S241656 in adults with advanced cancers that have certain gene changes (KRAS, BRAF, or related mutations). The drug is given alone or with other cancer treatments. The goal is to find safe doses and see if the drug shrinks tumors. …
Matched conditions: HISTIOCYTOSIS
Phase: PHASE1, PHASE2 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated May 26, 2026 07:11 UTC
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New hope for kids with rare blood disease: drug timing trial launched
Disease control Recruiting nowThis study looks at the best way to give the drug vemurafenib to children with a rare disease called histiocytosis that has not responded to standard treatments. The disease is linked to a specific gene change called BRAF. The goal is to find the right timing and dose to control …
Matched conditions: HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Anna Raciborska • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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New imaging and DNA test could transform Kids' cancer care
Knowledge-focused Recruiting nowThis study aims to improve how doctors diagnose and track histiocytosis, a rare disease that causes cell overgrowth, in children under 18. Researchers will use PET-CT scans with a special tracer and check tumor DNA in the blood to see if these methods can detect the disease earli…
Matched conditions: HISTIOCYTOSIS
Phase: PHASE3 • Sponsor: Anna Raciborska • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC