HISTIOCYTOSIS
Clinical trials for HISTIOCYTOSIS explained in plain language.
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New pill targets Hard-to-Treat cancers: early trial recruits 554 patients
Disease control Recruiting nowThis study tests an experimental oral drug called S241656 (BDTX-4933) in people with advanced solid tumors that have certain genetic changes (KRAS, BRAF, or other RAS/MAPK mutations). The trial has two parts: first, finding a safe dose, then testing how well it works alone or wit…
Matched conditions: HISTIOCYTOSIS
Phase: PHASE1, PHASE2 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope for kids with rare blood disorder: trametinib trial launches
Disease control Recruiting nowThis study tests the drug trametinib in children with histiocytosis, a rare blood disorder, that hasn't responded to standard treatments or has a specific genetic profile. The trial aims to find the best dose and timing to improve how long children live without their disease gett…
Matched conditions: HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Anna Raciborska • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New hope for kids with rare blood cancer: targeted drug trial launches
Disease control Recruiting nowThis study tests the drug vemurafenib in children with a rare blood disorder called histiocytosis that has a specific gene mutation (BRAF) and hasn't improved with standard treatments. The goal is to find the best dose and how long to give the drug to stop the disease from gettin…
Matched conditions: HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Anna Raciborska • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New imaging test could spot rare childhood disease sooner
Diagnosis Recruiting nowThis study aims to improve how doctors diagnose and monitor histiocytosis, a rare disease that causes abnormal cell growth, in children under 18. Researchers will use a special imaging agent called fluorodeoxyglucose (18F-FDG) in PET-CT scans, along with genetic testing of tumor …
Matched conditions: HISTIOCYTOSIS
Phase: PHASE3 • Sponsor: Anna Raciborska • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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Massive study tracks hidden toll of rare immune diseases
Knowledge-focused Recruiting nowThis study follows 6,000 people with histiocytic disorders (like Langerhans cell histiocytosis) to understand long-term health problems, pain, mental health, and causes of death. Researchers compare participants to healthy controls to identify factors that lead to new health issu…
Matched conditions: HISTIOCYTOSIS
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC