HISTIOCYTOSIS
Clinical trials for HISTIOCYTOSIS explained in plain language.
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New hope for kids with stubborn histiocytosis: vemurafenib dose trial launched
Disease control Recruiting nowThis study is for children with a rare disease called histiocytosis that has not improved with standard treatments and who have a specific gene change (BRAF mutation). The goal is to find the best dose and timing of the drug vemurafenib to control the disease. About 25 children w…
Matched conditions: HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Anna Raciborska • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New hope for kids with rare blood disease: trametinib trial opens
Disease control Recruiting nowThis study is for children with a rare blood disorder called histiocytosis that hasn't responded to standard treatments. It tests different doses and timing of the drug trametinib to find the best way to control the disease. The goal is to improve how long children stay free of c…
Matched conditions: HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Anna Raciborska • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New pill targets hard-to-treat cancers with KRAS and BRAF mutations
Disease control Recruiting nowThis early-phase study tests an oral drug called S241656 in adults with advanced cancers that have certain gene changes (KRAS, BRAF, and others). The drug is given alone or with other cancer treatments. The goal is to find safe doses and see if the drug shrinks tumors. About 554 …
Matched conditions: HISTIOCYTOSIS
Phase: PHASE1, PHASE2 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New study aims to sharpen detection of rare childhood disease
Diagnosis Recruiting nowThis study is for children under 18 with or suspected to have histiocytosis, a rare disease where certain immune cells grow too much. Researchers will use a special PET-CT scan and genetic tests on tumor tissue and blood to better detect and track the disease. The goal is to impr…
Matched conditions: HISTIOCYTOSIS
Phase: PHASE3 • Sponsor: Anna Raciborska • Aim: Diagnosis
Last updated Apr 30, 2026 15:50 UTC