HIGH-GRADE B-CELL LYMPHOMA
Clinical trials for HIGH-GRADE B-CELL LYMPHOMA explained in plain language.
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New hope for japanese lymphoma patients as experimental drug enters trials
Disease control OngoingThis study tests a drug called epcoritamab in about 78 Japanese adults with B-cell lymphoma that has come back or not responded to treatment. The goal is to find the safest dose and see if the drug can shrink tumors. The study has two parts: first, finding the right dose, then te…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Genmab • Aim: Disease control
Last updated May 26, 2026 07:57 UTC
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New combo shows promise against tough lymphomas
Disease control OngoingThis study tests a new drug combination for people with aggressive types of lymphoma that haven't been treated yet. The treatment adds a targeted drug called polatuzumab vedotin to standard chemotherapy. The goal is to see if this combo can make more cancers disappear completely.…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Barbara Ann Karmanos Cancer Institute • Aim: Disease control
Last updated May 26, 2026 07:55 UTC
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New combo therapy shows promise for tough lymphoma
Disease control OngoingThis early-phase study tests whether adding the drug acalabrutinib to a type of immune cell therapy (CAR T-cells) can safely treat B-cell lymphoma, a cancer of the immune system. About 23 adults with certain aggressive or slow-growing lymphomas will receive the combination. The g…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated May 26, 2026 07:52 UTC
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New CAR-T therapy shows promise for Tough-to-Treat blood cancers
Disease control OngoingThis early-stage study is testing a new type of cell therapy called P-CD19CD20-ALLO1 for people with certain B-cell cancers (like diffuse large B-cell lymphoma) that have come back or not responded to standard treatments. The therapy uses donor immune cells that are specially des…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Poseida Therapeutics, Inc. • Aim: Disease control
Last updated May 26, 2026 07:48 UTC
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Could a Pre-Treatment drug make CAR-T work better for tough lymphomas?
Disease control TerminatedThis study tests whether giving a drug called E7777 before standard CAR-T cell therapy can help people with relapsed or hard-to-treat large B-cell lymphoma. About 30 participants will receive E7777 followed by chemotherapy and an approved CAR-T product. The goal is to find the sa…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated May 26, 2026 07:23 UTC
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New CAR T-Cell therapy shows promise for Tough-to-Treat lymphoma
Disease control OngoingThis study tests a new type of CAR T-cell therapy for adults with B-cell lymphoma that has come back or not responded to treatment. The therapy uses a patient's own immune cells, modified to better target and kill cancer cells. The main goals are to find the safest dose and see i…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New combo therapy shows promise for Tough-to-Treat lymphoma
Disease control OngoingThis early-phase study tests whether adding the drug mosunetuzumab to standard chemotherapy is safe and effective for people with aggressive B-cell lymphoma that has returned or not responded to prior treatment. About 24 participants will receive one of two chemotherapy backbones…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Can a quick radiation boost make CAR t work better for tough lymphomas?
Disease control OngoingThis early-phase study looks at whether giving low-dose radiation before CAR T-cell therapy is practical and safe for people with B-cell lymphoma that has returned or not responded to treatment. About 33 adults will receive radiation to shrink tumors while waiting for their CAR T…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: University of Nebraska • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Tiny chip could spot lymphoma return early
Knowledge-focused OngoingThis study tests a nanochip technology to see if it can better monitor how well treatment is working and detect if lymphoma comes back in people with diffuse large B-cell lymphoma. About 73 participants will provide blood samples during their standard chemotherapy. The goal is to…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 07:50 UTC