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New antibody therapy targets hard-to-treat lymphomas in early trial

NCT ID NCT04594642

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 24 times

Summary

This early-phase study tests a new drug called AZD0486 in about 227 people with B-cell non-Hodgkin lymphoma, including types like diffuse large B-cell and follicular lymphoma. The drug is a special antibody that helps the immune system attack cancer cells. The main goals are to check safety, find the right dose, and see if it shrinks tumors. Participants must have already tried at least two other treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Tampa, Florida, 33612, United States

  • Research Site

    RECRUITING

    Louisville, Kentucky, 40207, United States

  • Research Site

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • Research Site

    RECRUITING

    Charlotte, North Carolina, 28204, United States

  • Research Site

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Research Site

    WITHDRAWN

    Portland, Oregon, 97239, United States

  • Research Site

    RECRUITING

    Pittsburgh, Pennsylvania, 15237, United States

  • Research Site

    RECRUITING

    Austin, Texas, 78704, United States

  • Research Site

    RECRUITING

    Houston, Texas, 77030, United States

  • Research Site

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Research Site

    WITHDRAWN

    Bedford Park, 5042, Australia

  • Research Site

    RECRUITING

    Heidelberg, 3084, Australia

  • Research Site

    RECRUITING

    Hobart, 7000, Australia

  • Research Site

    RECRUITING

    Melbourne, 3004, Australia

  • Research Site

    RECRUITING

    Chūōku, 104-0045, Japan

  • Research Site

    RECRUITING

    Kōtoku, 135-8550, Japan

  • Research Site

    RECRUITING

    Nagoya, 460-0001, Japan

  • Research Site

    RECRUITING

    Yamagata, 990-9585, Japan

  • Research Site

    RECRUITING

    Seoul, 03080, South Korea

  • Research Site

    RECRUITING

    Seoul, 05505, South Korea

  • Research Site

    RECRUITING

    Seoul, 06351, South Korea

  • Research Site

    RECRUITING

    Seoul, 06591, South Korea

  • Research Site

    RECRUITING

    Seoul, 120-752, South Korea

  • Research Site

    RECRUITING

    Kaohsiung City, 833401, Taiwan

  • Research Site

    RECRUITING

    Kweishan, 333, Taiwan

  • Research Site

    RECRUITING

    Tainan, 704, Taiwan

  • Research Site

    RECRUITING

    Taipei, 10002, Taiwan

Conditions

Explore the condition pages connected to this study.