HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Clinical trials for HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH) explained in plain language.
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New drug could help kids with inherited high cholesterol
Disease control Recruiting nowThis study tests a new medicine called enlicitide decanoate in children and teens with a genetic condition that causes very high cholesterol (HeFH). The goal is to see if the drug safely lowers bad cholesterol more than a placebo. About 153 participants will receive either the dr…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: PHASE2, PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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CRISPR therapy targets stubborn high cholesterol in first human trial
Disease control Recruiting nowThis study is testing a new treatment called CTX310, which uses CRISPR gene editing to turn off a gene linked to high cholesterol and fats. It is for adults aged 18 to 75 whose lipid levels remain high despite standard treatments. The goal is to see if the therapy is safe and can…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: PHASE1 • Sponsor: CRISPR Therapeutics AG • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New study screens newborns for inherited high cholesterol
Knowledge-focused Recruiting nowThis study aims to find different types of familial hypercholesterolemia (FH) in newborns. Parents will provide a cheek swab for genetic testing, and babies will have five blood samples collected over two years. The goal is to better understand and diagnose this inherited conditi…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC