CRISPR therapy targets stubborn high cholesterol in first human trial
NCT ID NCT07491172
First seen Mar 24, 2026 · Last updated May 19, 2026 · Updated 4 times
Summary
This study is testing a new treatment called CTX310, which uses CRISPR gene editing to turn off a gene linked to high cholesterol and fats. It is for adults aged 18 to 75 whose lipid levels remain high despite standard treatments. The goal is to see if the therapy is safe and can lower harmful blood fats, potentially reducing heart disease risk.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site 1
RECRUITINGAdelaide, 5000, Australia
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Research Site 10
NOT_YET_RECRUITINGJacksonville, Florida, 32216, United States
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Research Site 11
NOT_YET_RECRUITINGPort Orange, Florida, 32127, United States
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Research Site 12
NOT_YET_RECRUITINGPortland, Oregon, 97239, United States
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Research Site 13
NOT_YET_RECRUITINGHigh Point, North Carolina, 27260, United States
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Research Site 14
NOT_YET_RECRUITINGDurham, North Carolina, 27710, United States
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Research Site 15
NOT_YET_RECRUITINGBrisbane, 4064, Australia
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Research Site 16
NOT_YET_RECRUITINGBrisbane, Australia
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Research Site 17
NOT_YET_RECRUITINGOrlando, Florida, 32789, United States
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Research Site 18
NOT_YET_RECRUITINGCambridge, United Kingdom
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Research Site 2
RECRUITINGMelbourne, 3168, Australia
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Research Site 3
RECRUITINGHeidelberg, 3084, Australia
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Research Site 4
RECRUITINGChristchurch, 8011, New Zealand
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Research Site 5
RECRUITINGAuckland, 2025, New Zealand
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Research Site 6
RECRUITINGLondon, SE1 1YR, United Kingdom
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Research Site 7
NOT_YET_RECRUITINGCamperdown, 2050, Australia
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Research Site 8
NOT_YET_RECRUITINGLondon, E1 1BB, United Kingdom
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Research Site 9
NOT_YET_RECRUITINGCleveland, Ohio, 44195, United States
Conditions
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