Heterozygous familial hypercholesterolemia (HEFH)
Clinical trials for Heterozygous familial hypercholesterolemia (HEFH) explained in plain language.
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Can a monthly shot keep Kids' inherited high cholesterol in check for years?
Disease control Not yet recruitingThis trial is testing whether a monthly injection of lerodalcibep (Lerochol) can safely and effectively lower LDL cholesterol over three years in children and adolescents aged 6 to 17 with heterozygous familial hypercholesterolemia (HeFH), an inherited condition causing very high…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase 3 • Sponsor: LIB Therapeutics LLC • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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New shot could tame inherited high cholesterol
Disease control Not yet recruitingThis Phase III trial tests QLC7401, a new RNA-based drug, in 120 adults with heterozygous familial hypercholesterolemia (a genetic condition causing very high cholesterol). Participants already on cholesterol medication will receive either QLC7401 or a placebo injection. The stud…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase 3 • Sponsor: Qilu Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC