HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Clinical trials for HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH) explained in plain language.
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New drug could help kids with genetic high cholesterol
Disease control Recruiting nowThis study tests a new medicine called enlicitide decanoate in children and teens with a genetic condition that causes very high cholesterol (heterozygous familial hypercholesterolemia). The goal is to see if the drug is safe, tolerable, and lowers bad cholesterol more than a pla…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: PHASE2, PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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CRISPR injection targets stubborn high cholesterol in first human trial
Disease control Recruiting nowThis early-phase study tests a single-dose CRISPR treatment (CTX310) designed to edit a gene that controls fat levels in the blood. It is for adults aged 18 to 75 with severe high cholesterol or triglycerides that do not improve with standard medications. The main goal is to chec…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: PHASE1 • Sponsor: CRISPR Therapeutics AG • Aim: Disease control
Last updated May 04, 2026 16:19 UTC
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New study screens newborns for inherited high cholesterol
Knowledge-focused Recruiting nowThis study aims to find different types of familial hypercholesterolemia (FH) in newborns. Parents will provide a cheek swab for genetic testing, and babies will have five blood samples collected over two years. The goal is to better understand and diagnose this inherited conditi…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC