HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Clinical trials for HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH) explained in plain language.
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New daily pill could help kids with inherited high cholesterol
Disease control Recruiting nowThis study tests a daily pill called enlicitide decanoate in 153 children and teens with heterozygous familial hypercholesterolemia (HeFH), a genetic condition causing very high cholesterol. The goal is to see if the drug safely lowers LDL cholesterol more than a placebo. Researc…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: PHASE2, PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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CRISPR therapy takes aim at stubborn high cholesterol in first human trial
Disease control Recruiting nowThis early-stage trial tests a new CRISPR-based treatment called CTX310 for people with severe cholesterol and triglyceride problems that don't improve with standard therapies. The treatment uses a tiny fat bubble to deliver gene-editing tools that turn off a gene linked to high …
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: PHASE1 • Sponsor: CRISPR Therapeutics AG • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Heart scan study aims to predict artery disease in High-Risk patients
Knowledge-focused Recruiting nowThis study follows 300 adults aged 30–60 with genetically confirmed familial hypercholesterolemia, a condition causing very high cholesterol. Researchers use CT scans to see how coronary artery plaques change over 5 years. The goal is to better understand disease progression and …
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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New study screens newborns for inherited high cholesterol
Knowledge-focused Recruiting nowThis study aims to identify different types of familial hypercholesterolemia (FH) in infants and newborns. Expectant parents with FH will provide a cheek swab for genetic testing, and their babies will have 5 blood samples collected over 2 years. The goal is to improve early dete…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC