HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Clinical trials for HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH) explained in plain language.
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New hope for kids with genetic high cholesterol
Disease control Recruiting nowThis study is testing a new drug called enlicitide decanoate to see if it is safe and effective for lowering bad cholesterol in children and teenagers with a genetic condition called heterozygous familial hypercholesterolemia (HeFH). Researchers will measure how the drug works in…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: PHASE2, PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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CRISPR One-Shot aims to fix stubborn cholesterol for good
Disease control Recruiting nowThis is the first human trial of an experimental one-time treatment called CTX310, which uses CRISPR gene-editing technology. It aims to permanently lower harmful cholesterol and fat levels in the blood of adults whose levels don't respond well to existing medications. The study …
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: PHASE1 • Sponsor: CRISPR Therapeutics AG • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Catching a silent killer at birth: new study hunts for inherited heart risk in babies
Diagnosis Recruiting nowThis study aims to find babies born with a genetic condition that causes very high cholesterol, called familial hypercholesterolemia (FH). Researchers will work with expecting parents who have FH to test their newborns with cheek swabs and small blood samples. The goal is to iden…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH)
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Diagnosis
Last updated Mar 31, 2026 12:11 UTC