New drug could help kids with genetic high cholesterol

NCT ID NCT07058077

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This study tests a new medicine called enlicitide decanoate in children and teens with a genetic condition that causes very high cholesterol (heterozygous familial hypercholesterolemia). The goal is to see if the drug is safe, tolerable, and lowers bad cholesterol more than a placebo. About 153 participants will receive either the drug or a placebo, and researchers will monitor cholesterol levels and side effects over time.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam UMC, locatie AMC ( Site 1000)

    RECRUITING

    Amsterdam, North Holland, 1105 AZ, Netherlands

    Contact Phone: •••-•••-••••

  • Beijing Anzhen Hospital. Capital Medical University ( Site 1917)

    RECRUITING

    Beijing, Beijing Municipality, 100029, China

    Contact Phone: •••-•••-••••

  • Birmingham Childrens Hospital ( Site 1501)

    RECRUITING

    Birmingham, B4 6NH, United Kingdom

    Contact Phone: •••-•••-••••

  • COMPLEJO HOSPITALARIO DE NAVARRA ( Site 1302)

    RECRUITING

    Pamplona, Navarre, 31009, Spain

    Contact Phone: •••-•••-••••

  • Children's Healthcare of Atlanta Cardiology ( Site 0026)

    RECRUITING

    Atlanta, Georgia, 30329, United States

    Contact Phone: •••-•••-••••

  • Children's National Medical Center ( Site 0015)

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-••••

  • Cincinnati Children's Hospital Medical Center ( Site 0016)

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-••••

  • Clinica de la Costa S.A.S. ( Site 0400)

    RECRUITING

    Barranquilla, Atlántico, 080020, Colombia

    Contact Phone: •••-•••-••••

  • Excel Medical Clinical Trials ( Site 0008)

    RECRUITING

    Boca Raton, Florida, 33434, United States

    Contact Phone: •••-•••-••••

  • Fundacion Valle del Lili ( Site 0403)

    RECRUITING

    Cali, Valle del Cauca Department, 760032, Colombia

    Contact Phone: •••-•••-••••

  • Fundación Cardiovascular de Colombia ( Site 0402)

    RECRUITING

    Piedecuesta, Santander Department, 681017, Colombia

    Contact Phone: •••-•••-••••

  • Hospital Clinico Universitario de Santiago de Compostela ( Site 1300)

    RECRUITING

    Santiago de Compostela, La Coruna, 15706, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitario Central de Asturias ( Site 1303)

    RECRUITING

    Oviedo, Asturias, Principado de, 33011, Spain

    Contact Phone: •••-•••-••••

  • Incor - Instituto do Coracao ( Site 0200)

    RECRUITING

    São Paulo, 05403900, Brazil

    Contact Phone: •••-•••-••••

  • Monash Children s Hospital ( Site 1603)

    RECRUITING

    Clayton, Victoria, 3168, Australia

    Contact Phone: •••-•••-••••

  • National University Hospital-Paediatrics ( Site 1800)

    RECRUITING

    Singapore, Central Singapore, 117599, Singapore

    Contact Phone: •••-•••-••••

  • Nemours/Alfred I. duPont Hospital for Children ( Site 0001)

    RECRUITING

    Wilmington, Delaware, 19803, United States

    Contact Phone: •••-•••-••••

  • New Childrens Hospital ( Site 0800)

    RECRUITING

    Helsinki, Uusimaa, 00029, Finland

    Contact Phone: •••-•••-••••

  • New Zealand Clinical Research (Christchurch) ( Site 1700)

    RECRUITING

    Christchurch, Canterbury, 8011, New Zealand

    Contact Phone: •••-•••-••••

  • Oncomédica S.A.S ( Site 0401)

    RECRUITING

    Montería, Departamento de Córdoba, 230002, Colombia

    Contact Phone: •••-•••-••••

  • Shanghai Children's Medical Center ( Site 1918)

    RECRUITING

    Shanghai, Shanghai Municipality, 200120, China

    Contact Phone: •••-•••-••••

  • Sheffield Childrens Hospital ( Site 1503)

    RECRUITING

    Sheffield, S10 2TH, United Kingdom

    Contact Phone: •••-•••-••••

  • The Children's Hospital of Zhejiang University School of Medicine ( Site 1905)

    RECRUITING

    Hangzhou, Zhejiang, 310057, China

    Contact Phone: •••-•••-••••

  • UZ Antwerpen ( Site 0601)

    RECRUITING

    Edegem, Antwerpen, 2650, Belgium

    Contact Phone: •••-•••-••••

  • Universidade Federal Do Ceara ( Site 0201)

    RECRUITING

    Fortaleza, Ceará, 60430270, Brazil

    Contact Phone: •••-•••-••••

  • West Virginia University ( Site 0013)

    RECRUITING

    Morgantown, West Virginia, 26506, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.