HEPATOCELLULAR CANCER

This early-phase trial tested a new approach for advanced liver cancer that has not responded to standard treatments. Researchers took participants' own immune cells, modified them in a lab to target a protein called AFP found on cancer cells, and infused them back after a short …

This phase 2 trial tested whether adding hydroxychloroquine, a drug used for arthritis and malaria, to the standard liver cancer drug sorafenib could improve outcomes. The study enrolled 64 adults with advanced liver cancer who could not have surgery or a transplant. Researchers …

This early-stage study tested a new drug combination (vobramitamab duocarmazine plus lorigerlimab) in 31 people with advanced solid tumors like prostate, melanoma, and pancreatic cancer. The main goal was to check safety and find the right dose. Participants received the drugs ev…

This study looked at side effects of the drug Cabometyx in 263 Japanese adults with advanced liver cancer that had worsened after other treatments. Doctors monitored participants for 12 months to record any serious or severe side effects. The goal was to understand the drug's saf…

This study looked at whether a breath test could help detect liver fibrosis, cirrhosis, or liver cancer. Researchers collected breath samples from 56 patients with known or suspected liver disease and analyzed them for specific chemical markers. The goal was to see if the test co…

This study tested whether adding a palliative care team to standard surgical care improves quality of life for patients with gastrointestinal cancers and their families. 379 patients and their companions were randomly assigned to receive either surgeon care alone or surgeon care …

This study tested two approaches to bring palliative care (comfort-focused care) to people with end-stage liver disease. About 1,500 adults from 19 U.S. centers took part. One group had direct access to a palliative care specialist; the other group saw a liver doctor specially tr…

This study looked at whether taking pregabalin (a pain medication) before a liver cancer procedure called radiofrequency ablation can help control pain afterward. 70 adults with liver cancer took part. The goal was to see if this approach reduces pain levels after the treatment.