HEPATITIS C

This study tested a new combination of two oral drugs, bemnifosbuvir and ruzasvir, in 275 adults with chronic hepatitis C. The main goal was to see if the treatment could clear the virus from the blood 12 weeks after finishing the medication, which would mean a cure. The approach…

This study tested a new drug called MP-424 combined with two standard medications (peginterferon alfa-2b and ribavirin) in 32 adults with genotype 1 hepatitis C who had not responded to earlier treatment. The main goal was to see if the virus could be cleared from the blood 24 we…

This study tested two methods for offering HIV, hepatitis C, and addiction medications to 100 people who inject drugs. Participants received either standard care or a tele-harm reduction approach to start treatment quickly. The goal was to see which method helped more people achi…

This early-phase study tested a new drug called MP-424 alongside standard hepatitis C treatments (peginterferon alfa-2b and ribavirin) in 20 adults with genotype 1b chronic hepatitis C. The main goal was to check the drug's safety and how it moves through the body. Researchers al…

This early study tested a drug called MP-424 in 15 people with chronic hepatitis C (genotype 1b). The goal was to see if the drug could clear the virus and how safe it was. Participants had not taken other hepatitis C treatments before. The main measure was whether the virus stay…

This study tested whether livers from donors with hepatitis C could be safely transplanted into people without hepatitis C. Five patients received such livers and were then treated with the antiviral drug Epclusa to prevent infection. The goal was to expand the donor pool and red…

This study tested a new drug called MP-424 combined with two standard medicines (peginterferon and ribavirin) in 189 adults with untreated genotype 1 hepatitis C. The goal was to see if the combination could clear the virus from the blood 24 weeks after treatment ended. Participa…

This study tested whether a smartphone app (GeoPassport) plus incentives and peer mentors could help men who have sex with men and transgender women leaving jail get HIV prevention services like PrEP and testing. 233 participants were split into two groups: one got routine case m…

This study tested a program to help 219 incarcerated individuals with HIV, hepatitis C, or substance use disorder transition from prison to community healthcare. Participants worked with a nurse case manager before and after release to plan and coordinate their care. The goal was…

This study looks at hepatitis C virus (HCV) infection in blood donors who tested positive for it. The goal is to learn how the virus spreads, how many people develop liver disease, and what happens over time. About 805 participants will give blood samples and answer health questi…

This study offered a quick hepatitis C test to 1,500 women aged 50-74 who were already coming in for breast cancer screening. The goal was to see how many women would agree to the extra test and to find undiagnosed hepatitis C cases. Women who tested positive were then guided to …

This study looked at how many people held in the Nîmes administrative detention center have HIV, hepatitis B, or hepatitis C. Researchers used rapid tests to get results quickly, since many detainees leave before standard lab results come back. The goal was to find out how common…

This study looked at 10 adults with chronic hepatitis C to find human proteins stuck to the virus. By identifying these proteins, researchers hope to learn how the virus spreads and find new ways to stop it. The study did not test any treatment, only observed the virus in blood s…

This study tested 892 African and Asian immigrants in Minnesota for hepatitis B and C to understand how common these infections are and how they increase the risk of liver cancer. Researchers also looked at viral genetics and immune responses. No treatment was given; the goal was…