HEPATITIS C

This study is testing a hepatitis C medication (glecaprevir/pibrentasvir) in 30 pregnant women who have hepatitis C, with or without HIV. The goal is to see if the drug is safe and works well during pregnancy, potentially curing the mother and preventing the baby from getting the…

This study looks at whether it is possible and acceptable to start hepatitis C treatment during pregnancy in women who have a history of drug use. About 50 pregnant adults will take the medication glecaprevir-pibrentasvir and be followed for one year. Researchers will measure how…

This project aims to make hepatitis C testing and treatment more accessible for people who visit drug treatment clinics and needle exchange programs. Researchers will work with 6,000 adults who have a history of injecting drug use to help them start treatment. The goal is to crea…

This study checks if it is safe to use hearts from donors who have hepatitis C for heart transplants. About 500 people who received such a heart will be followed to see how they do, including survival, organ rejection, and whether the hepatitis C is cured. The goal is to see if u…

This study compares a new oral medication, Bemnifosbuvir-Ruzasvir, to the current standard treatment, Sofosbuvir-Velpatasvir, for adults with chronic hepatitis C. About 880 participants who have not taken similar drugs before will receive one of the two treatments. The main goal …

This study is testing whether a dried blood spot (a drop of blood on a card) can effectively screen for hepatitis B, hepatitis C, and AIDS in people who use drugs. The goal is to make screening easier and more accessible for this group. Researchers will enroll 500 current or form…

This study follows up to 8,050 people with or at risk for liver disease (like hepatitis B, C, or D) to learn how these conditions develop and progress. Participants give blood and urine samples, get yearly liver ultrasounds, and may have optional biopsies. The goal is to gather i…

This study looks at the medical records of 15,000 people to understand how chronic liver diseases (like hepatitis, fatty liver, and cirrhosis) are connected to other health problems. Researchers will track who develops liver cancer or serious liver complications over time. The go…

This study aims to see if a simple finger-stick test can help more people get diagnosed and treated for hepatitis C. Researchers will test 60,000 adults at high risk, such as those in drug treatment clinics or prisons. Participants get tested once and fill out a survey, but do no…

This study collects DNA samples from 1200 adults receiving routine care at the University of Chicago. Researchers test for genetic differences that could affect how patients respond to certain medications, including risk of side effects. The results are shared with their doctors,…

This study tests a smartphone app designed to teach emergency room patients about hepatitis C (HCV). The app provides personalized information about liver health, HCV knowledge, and steps to get care. Researchers want to see if using the app helps patients understand their condit…