HEMODYNAMIC INSTABILITY

This study tests whether combining mild electrical nerve stimulation (TENS) with isometric exercise can improve blood pressure in people with resistant hypertension—high blood pressure that doesn't respond to multiple medications. Fifty men and women aged 50 to 60 will be split i…

This study tests whether a short, guided breathing exercise done right before spinal anesthesia can help prevent a dangerous drop in blood pressure during planned C-sections. About 150 pregnant women will be randomly assigned to either do the breathing exercise or receive standar…

This study looks at how different monitors detect blood loss in healthy adults. Researchers will use a special device to safely lower blood volume and track changes in pulse and blood flow. The goal is to find the most reliable spot on the body to monitor for low blood volume, wh…

This study looks at whether using a special heart ultrasound (called transesophageal echocardiography) during emergencies helps doctors better treat critically ill patients, including those in cardiac arrest or shock. Researchers will track 1,000 adults in the ER and ICU to see i…

This study is testing a new monitoring platform in 100 adults having heart or liver transplant surgery. The goal is to collect data to help improve the device, not to treat a disease. Participants must be at least 18 years old and already scheduled for a pulmonary artery catheter…

This study tests whether an artificial intelligence system can help doctors better manage blood pressure and fluid levels during complex ovarian cancer surgery. The approach aims to reduce complications like kidney injury and fluid buildup in the lungs. About 52 adults scheduled …

This study looks at 30 infants, aged 3-8 months, having surgery to correct craniosynostosis (early skull bone fusion). Researchers want to see if a new monitoring method (PRAM) can better detect dangerous changes in blood pressure and blood loss compared to standard monitoring. T…

This study looks at whether using a special monitoring system (MostCare) during ERCP procedures under sedation can help prevent problems like low blood pressure or low oxygen. About 32 adults at higher risk for complications will take part. The goal is to see if advanced monitori…

This study watches children from birth to 18 years old who need anesthesia for an MRI. It measures how different anesthetics change blood flow and oxygen use in the brain. The goal is to learn, not to treat. Up to 1,000 children will join.

This study compares a non-invasive continuous blood pressure monitor (ClearSight) to the standard arterial catheter in 50 adults undergoing coil embolization for unruptured brain aneurysms. The goal is to see if the non-invasive method can reliably detect dangerous blood pressure…

This study aims to create a complete artificial blood substitute that can be used when real blood is not available. Researchers will combine lab-made oxygen carriers, plasma, and platelets to mimic natural whole blood. The work is done in the lab with 250 healthy adults providing…