HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Clinical trials for HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM explained in plain language.
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New hope for kids with tough cancers: trial tests precision drug
Disease control OngoingThis study is testing how well a drug called selpercatinib works for children and young adults with advanced or hard-to-treat cancers that have a specific genetic change in the RET gene. The drug is designed to block the growth of cancer cells with this change. Participants take …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Poop pills tested to stop deadly transplant complication
Disease control OngoingThis study is testing whether taking capsules containing processed, healthy stool (fecal microbiota) can prevent severe graft-versus-host disease (GVHD) in adults who have received a bone marrow transplant. GVHD is a serious and common complication where the donor's immune cells …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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New drug duo targets Hard-to-Treat rare cancers
Disease control OngoingThis study is testing whether a combination of two oral drugs, talazoparib and temozolomide, can shrink advanced rare cancers that have spread and for which standard treatments have stopped working. The trial aims to see if this drug pair can stop tumor growth by damaging cancer …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Targeted drug trial offers hope for Tough-to-Treat cancers with rare mutations
Disease control OngoingThis study is testing whether the drug vismodegib can help control advanced cancers that have specific genetic mutations and have stopped responding to standard treatments. The trial includes 35 adults with solid tumors, lymphoma, or multiple myeloma that have spread or are resis…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug targets Cancer's genetic weakness in Hard-to-Treat cases
Disease control OngoingThis study is testing whether a drug called copanlisib can shrink or stop the growth of advanced cancers that have a specific genetic change called a PIK3CA mutation. The drug works by blocking a protein that cancer cells need to grow. The trial includes 35 adults with various ad…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Could a simple probiotic shield kids from dangerous transplant complication?
Prevention OngoingThis study is testing whether a specific probiotic (Lactobacillus plantarum) can prevent a serious complication called acute graft-versus-host disease (GvHD) in children, teens, and young adults receiving a donor stem cell transplant. GvHD happens when the new donor cells attack …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention
Last updated Apr 03, 2026 14:41 UTC
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Blood test could guide drug to stop transplant rejection
Prevention TerminatedThis study is testing if a drug called ruxolitinib can prevent a serious complication called chronic graft-versus-host disease (GVHD) in patients who have received a bone marrow transplant for blood cancer. Researchers will first use a blood test to identify patients at high risk…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Prevention
Last updated Mar 23, 2026 15:18 UTC
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Broccoli pill trial aims to shield firefighters from cancer
Prevention OngoingThis study is testing whether a daily broccoli seed and sprout extract can boost the body's natural ability to clear out cancer-causing chemicals that firefighters breathe in during their work. It involves 66 active, non-smoking firefighters who will take either the broccoli extr…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated Mar 02, 2026 15:21 UTC
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Shining light on transplant pain
Symptom relief OngoingThis study looks at whether a light therapy treatment helps reduce painful mouth sores and other oral problems in cancer patients receiving a stem cell transplant. Researchers are observing 6 patients and the nurses who give the treatment to see how well it works. The goal is to …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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Can a common antidepressant fight cancer fatigue?
Symptom relief OngoingThis study is testing whether the medication bupropion can help reduce severe fatigue in cancer survivors. Over 400 participants who have finished their main cancer treatments will receive either bupropion or a placebo pill for 13 weeks. Researchers will measure changes in fatigu…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief
Last updated Apr 02, 2026 15:03 UTC
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Can a simple scent ease the fear of cancer biopsies?
Symptom relief TerminatedThis study is testing whether smelling lavender or similar scents can help reduce pain and anxiety for cancer patients during bone marrow biopsy procedures. Researchers want to see if this simple, drug-free approach can make these uncomfortable tests easier to tolerate. The trial…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Mar 16, 2026 15:25 UTC
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Scientists monitor how cancer treatments affect Kids' vaccine protection
Knowledge-focused OngoingThis study observes how children, teens, and young adults with cancer respond to COVID-19 vaccines. Researchers are tracking immune system reactions over two years to understand how cancer treatments affect vaccine protection. The study involves blood tests and surveys but does n…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Cancer Treatment's hidden side effect: doctors track balance problems
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how immunotherapy cancer treatments affect patients' balance and hearing. Researchers will follow 50 adult cancer patients for one year, testing their balance and hearing before they start treatment and again at 3, 6, and 12 months. The goal is to ga…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Major study tracks COVID-19 impact on 1,877 cancer patients
Knowledge-focused OngoingThis study observes cancer patients who get COVID-19 to understand how the virus affects their cancer treatment and recovery. Researchers collect blood samples and medical information from 1,877 participants over two years to learn about immune responses and treatment changes. Th…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Mayo clinic launches major survey to tackle cancer screening gaps in prisons
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand cancer screening awareness and barriers among incarcerated women. Researchers will survey 1,200 women at a Florida prison to learn about their knowledge, screening history, and challenges. The information will be used to create a digital education pr…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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New training aims to help cancer clinics better care for older patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing whether providing training and support to cancer clinic staff helps them deliver a special health check-up for older adults starting new cancer treatments. The check-up looks at a patient's overall physical health, support network, and daily life impact, not…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC