HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Clinical trials for HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM explained in plain language.
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New hope for kids with rare cancers: targeted drug shows promise in early trial
Disease control OngoingThis study tests a drug called selpercatinib (LOXO-292) in children and young adults (ages 1 to 21) with advanced cancers that have a specific genetic change in the RET gene. The goal is to see if the drug can shrink tumors or stop them from growing. The trial is for patients who…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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Firefighters' secret weapon against cancer? broccoli extract shows promise in new trial
Disease control OngoingThis study tests whether a daily broccoli seed and sprout extract (BSSE) can boost firefighters' natural ability to remove cancer-causing chemicals like benzene from their bodies. 72 firefighters who do not smoke will take either the extract or a placebo for 12 weeks. Researchers…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New drug targets genetic weakness in Hard-to-Treat cancers
Disease control OngoingThis study tests a drug called copanlisib in people whose advanced cancers have a specific genetic change (PIK3CA mutation). The drug blocks a protein that helps cancer cells grow. Researchers want to see if it can shrink tumors or stop them from growing. About 35 adults with var…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 18, 2026 12:04 UTC
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New drug combo shows promise for rare, Hard-to-Treat cancers
Disease control OngoingThis study tests whether a combination of two drugs, talazoparib and temozolomide, can shrink advanced rare cancers or stop them from growing. The trial includes 14 adults with rare solid tumors that have not responded to standard treatments. Talazoparib blocks a protein that hel…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 18, 2026 11:59 UTC
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New hope for hard-to-treat cancers with rare gene mutations
Disease control OngoingThis study tests a drug called vismodegib in people with advanced or treatment-resistant cancers (solid tumors, lymphoma, or multiple myeloma) that have specific changes in the SMO or PTCH1 genes. The drug blocks a protein that helps cancer grow. The goal is to see if the drug ca…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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Poop pills may shield stem cell patients from deadly complication
Prevention OngoingThis study tests whether giving patients processed fecal material (fecal microbiota transplantation) by mouth after a stem cell transplant can prevent severe graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. The trial involves 1…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Prevention
Last updated May 26, 2026 05:56 UTC
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Probiotic shows promise in preventing deadly transplant complication in kids
Prevention OngoingThis study tests whether a probiotic called Lactobacillus plantarum can prevent a serious gut condition called graft-versus-host disease (GvHD) in children receiving a donor stem cell transplant. About 173 children with blood cancers or other blood disorders are taking part. The …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention
Last updated May 18, 2026 12:02 UTC
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Can an antidepressant beat cancer fatigue? new trial investigates
Symptom relief OngoingThis phase 3 trial tests whether bupropion, a drug used for depression and smoking cessation, can reduce fatigue in cancer survivors. About 422 adults who have completed cancer treatment and still have moderate to severe fatigue will receive either bupropion or a placebo. The stu…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief
Last updated May 26, 2026 05:59 UTC
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Lavender scent may soothe biopsy pain without opioids
Symptom relief TerminatedThis study tests whether smelling lavender oil can help cancer patients feel less pain and anxiety during a bone marrow biopsy. About 45 adults with cancer who are nervous about the procedure will try the aromatherapy. The goal is to find a safe, non-drug way to make the experien…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated May 26, 2026 05:56 UTC
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Light therapy may soothe mouth pain for transplant patients
Symptom relief OngoingThis study looks at whether a special light treatment (photobiomodulation) can help reduce mouth sores, pain, taste changes, and dry mouth in patients getting a stem cell transplant. Six adult patients are being observed, some who received the light therapy and some who did not. …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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Cancer patients with COVID-19: new study tracks their journey
Knowledge-focused OngoingThis study follows nearly 1,900 cancer patients who tested positive for COVID-19. Researchers collect blood samples, medical records, and images to see how the virus impacts their cancer treatment and overall health. The goal is to learn which factors make COVID-19 more severe in…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 26, 2026 05:58 UTC
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Cancer treatment may throw you off balance – new study investigates
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how immunotherapy drugs affect balance and hearing in people with cancer. Researchers will test 50 patients before, during, and after treatment to see if their balance changes. The goal is to better understand side effects so doctors can help patients manage t…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 05:55 UTC
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Marijuana withdrawal under the microscope in transplant patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how often cannabis withdrawal happens and what symptoms appear in patients hospitalized for bone marrow transplant or CAR-T therapy. Researchers will track 300 adults at Mayo Clinic using a symptom questionnaire. The goal is to better understand withdrawal in …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 05:46 UTC
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Can a simple Check-Up improve cancer care for seniors?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether training cancer clinic staff to give a special health check-up (called a geriatric assessment) helps older adults (65+) starting a new cancer therapy. The check-up covers physical health, daily life, and support networks. Researchers want to see if thi…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 26, 2026 05:46 UTC
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Cancer Patients' vaccine response under microscope
Knowledge-focused OngoingThis study tracks how the immune systems of children, teens, and young adults with cancer respond to COVID-19 vaccines. Cancer and its treatments can weaken immunity, so researchers want to see if factors like vaccine type, timing, and booster shots affect protection. About 549 p…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC
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Prison health study seeks to boost cancer screening for incarcerated women
Knowledge-focused ENROLLING_BY_INVITATIONThis study surveys 1,200 incarcerated women at a Florida prison to learn about their cancer screening history, risk factors, and barriers to care. The goal is to create a digital education module to improve cancer awareness and screening in prisons. Participants fill out a 15-min…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC