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New digital coaching aims to ease cancer pain and cut opioid risks

NCT ID NCT06198010

Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 03, 2026 · Updated 2 times

Summary

This study tests a program called ASCENT that helps cancer survivors manage pain using an educational guide and coaching from community health workers and pain care managers. The goal is to improve pain control and lower the risk of opioid misuse. About 660 adults with cancer-related pain who live in rural areas or identify as Hispanic will take part.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

680 people

The number who actually took part.

Started

Feb 2024

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * A qualifying liquid or solid cancer diagnosis with visits at a participating Mayo site in the past 15 years * Including malignant hematology * Lymphoma * Myeloma * Chronic leukemias * Age \>= 18 * Numeric Rating Scale (NRS) pain score of \>= 5/10 * Pain that developed or worsened following cancer diagnosis * Fit the description of either rural or Hispanic or both Exclusion Criteria: * Patient Health Questionnaire - 8 (PHQ8) score of \>= 13 * Hospice enrollment * Skilled nursing facility, inpatient rehabilitation facility, or long-term care placement * Encounters with Palliative Care or the Pain Clinic in the past two months or upcoming two months * Any mention of hospice referral in medical oncology encounter notes (assess through textual search of the Mayo Data Explorer) * Affirmative response to, "Are you usually confined to a bed or chair more than a third of your waking hours because of your health?" * Currently homeless * Do not feel safe in their home * New or worsening chest pain, chest tightness, or chest pressure * Back pain that is associated with a new or worsening weakness, control of bowels/bladder, or difficulty walking * Lightheadedness, inability to keep down food or fluids, or vomiting blood or dark coffee-grounds-like material * New or worsening headaches that are associated with vision changes, nausea, balance issues, or problems with speech * Screens positive for use of non-cannabis drug use a a frequency of monthly or greater * Inability to engage with the intervention due to medical or psychological response

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Conditions

The condition(s) this trial relates to.

cancer chronic leukemia hematopoietic and lymphoid system neoplasm lymphoma plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hematopoietic and lymphatic system neoplasm Hematopoietic and lymphoid system neoplasm Malignant solid neoplasm

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.