HARM REDUCTION
Clinical trials for HARM REDUCTION explained in plain language.
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Can a TB drug help smokers kick the habit with E-Cigs?
Disease control CompletedThis study tested whether a medication called d-cycloserine, combined with using a Juul e-cigarette, helps smokers switch completely from regular cigarettes. Twenty-five adult smokers who wanted to switch took d-cycloserine daily for six weeks and used Juul as much as they liked.…
Matched conditions: HARM REDUCTION
Phase: PHASE2 • Sponsor: Rose Research Center, LLC • Aim: Disease control
Last updated Jun 22, 2026 11:58 UTC
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Nicotine swap helps smokers slash cigarettes in half
Disease control CompletedThis study looked at whether smokers who quickly respond to nicotine alternatives (like patches, e-cigarettes, or pouches) can keep smoking less or stop entirely for 6 months. 150 healthy adult smokers who reduced their smoking by at least half within 2 weeks were followed. The g…
Matched conditions: HARM REDUCTION
Phase: PHASE3 • Sponsor: Rose Research Center, LLC • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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Ohio courts hand out Life-Saving overdose prevention kits
Prevention CompletedThis study looked at whether giving fentanyl test strips and naloxone to people in Ohio drug courts could help prevent overdoses from stimulants mixed with opioids. Over 650 adults who used stimulants in the past 6 months took part. Researchers tracked how many people used the ki…
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: Nationwide Children's Hospital • Aim: Prevention
Last updated Jun 22, 2026 12:04 UTC
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App aims to curb chemsex risks in gay men
Knowledge-focused CompletedThis study tested a mobile app designed to help gay, bisexual, and other men who have sex with men reduce the negative effects of chemsex (using drugs like ecstasy or crystal meth during sex). The app was added to an existing PrEP tool. 25 participants who had used drugs in a sex…
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: National Cheng Kung University • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:49 UTC