Can a TB drug help smokers kick the habit with E-Cigs?
NCT ID NCT05994703
First seen Jan 22, 2026 · Last updated Jun 20, 2026 · Updated 23 times
Summary
This study tested whether a medication called d-cycloserine, combined with using a Juul e-cigarette, helps smokers switch completely from regular cigarettes. Twenty-five adult smokers who wanted to switch took d-cycloserine daily for six weeks and used Juul as much as they liked. The goal was to see if this approach could speed up learning new habits and reduce smoking.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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Rose Research Center
Charlotte, North Carolina, 28262, United States
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Rose Research Center
Raleigh, North Carolina, 27617, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
d-cycloserine (a medication) and Juul e-cigarette
What this could lead to
If it works, this could point toward a new way to help smokers switch to e-cigarettes and reduce harm from smoking.
What could go wrong
This is a very small, early Phase 2 trial with only 25 people. The results may not apply to everyone, and d-cycloserine can cause side effects like dizziness or drowsiness.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.