HARM REDUCTION
Clinical trials for HARM REDUCTION explained in plain language.
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Smokers switch: can E-Cigs or pouches cut cigarette use?
Disease control Recruiting nowThis study aims to see if e-cigarettes or oral nicotine pouches work better to help persistent smokers reduce their cigarette smoking. Researchers will enroll 200 adult smokers who have tried to quit before but haven't succeeded. Participants will be randomly assigned to use eith…
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Can a text and a friend cut overdose risk? new hospital program aims to find out
Disease control Recruiting nowThis study is testing a new support program called THRIVE for people leaving the hospital who have opioid use disorder. It aims to see if connecting patients with a trained peer specialist for in-person and text message support can help reduce dangerous overdoses and skin infecti…
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Life-Saving drug in a vending machine: new program aims to stop overdoses
Prevention Recruiting nowThis study is testing whether putting free naloxone (a medication that can reverse an opioid overdose) in community vending machines makes it easier for people to get it. The goal is to see if this method helps prevent overdose deaths by getting the medication to more people who …
Matched conditions: HARM REDUCTION
Phase: PHASE4 • Sponsor: University of Colorado, Denver • Aim: Prevention
Last updated Apr 03, 2026 22:41 UTC
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Schools try new approach instead of punishment for student drug use
Prevention Recruiting nowThis study is testing a new education program called iDECIDE for middle and high school students who recently broke their school's substance use rules. About 300 students will be randomly assigned to either take the 4-week iDECIDE classes right away or be placed on a waitlist. Th…
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Prevention
Last updated Apr 02, 2026 14:56 UTC
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NYC tests new strategy to fight overdoses in homeless shelters
Knowledge-focused Recruiting nowThis study aims to understand how a new harm reduction plan in New York City's homeless shelters affects overdoses and health. Researchers will look at shelter and health records for about 80 people and also interview shelter clients and staff. The goal is to learn what works to …
Matched conditions: HARM REDUCTION
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC