HARM REDUCTION
Clinical trials for HARM REDUCTION explained in plain language.
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New hope for hard-to-quit smokers: e-cigarettes and cytisine put to the test
Disease control Not yet recruitingThis study looks at whether e-cigarettes or a medicine called cytisine can help people who keep smoking even after trying nicotine patches and counseling. 6,000 adults who smoke at least 5 cigarettes a day will be randomly given either an e-cigarette starter kit or a 28-day suppl…
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New tool aims to prevent opioid overdose during tapering
Prevention Not yet recruitingThis study tests a clinical decision support tool that reminds doctors to follow CDC guidelines when reducing opioid doses in patients. About 200,000 primary care patients will be included. The goal is to lower the risk of withdrawal, overdose, and poisoning by encouraging safer …
Matched conditions: HARM REDUCTION
Sponsor: University of Colorado, Denver • Aim: Prevention
Last updated May 26, 2026 12:09 UTC
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Can a phone app help people in supportive housing stay stable?
Knowledge-focused Not yet recruitingThis study will test if a technology-based tool is helpful and easy to use for people living in supportive housing who also have substance use issues. The tool includes videos and rewards to teach skills like cognitive behavioral therapy and life skills. Researchers want to see i…
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: Oregon Research Behavioral Intervention Strategies, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 12:12 UTC
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New alert aims to curb opioid overdoses
Knowledge-focused Not yet recruitingThis study tests a computer alert that notifies doctors when a patient is about to move from short-term to long-term opioid use. The goal is to help doctors review the patient's pain and risks before prescribing more opioids. About 200,000 patients will take part, and researchers…
Matched conditions: HARM REDUCTION
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 26, 2026 12:05 UTC
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Smart alert aims to boost opioid addiction treatment in primary care
Knowledge-focused Not yet recruitingThis study tests whether a computer alert can help primary care doctors identify patients with opioid use disorder and guide them to prescribe effective medications like buprenorphine. About 200,000 patients will be involved, with some clinics getting the alert and others not. Th…
Matched conditions: HARM REDUCTION
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC