GRANULOMATOSIS WITH POLYANGIITIS
Clinical trials for GRANULOMATOSIS WITH POLYANGIITIS explained in plain language.
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Are cheaper versions of a key vasculitis drug just as safe and effective?
Disease control CompletedThis study looked at 201 Canadian patients with ANCA-associated vasculitis to see if biosimilar versions of rituximab work as well as the original drug. Researchers tracked disease control, side effects, and how long it took to get insurance approval for treatment. The goal is to…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 26, 2026 08:50 UTC
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Blood Test-Guided dosing could spare patients unnecessary infusions
Disease control CompletedThis study tested whether giving the drug rituximab only when blood markers (ANCA and CD19 cells) rise is as good as giving it on a fixed schedule to prevent relapses in people with ANCA-associated vasculitis. 166 adults who were already in remission took part. The goal was to se…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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Steroid showdown: low dose vs. no dose in rare disease trial
Disease control CompletedThis study looked at 159 people with a rare autoimmune disease called granulomatosis with polyangiitis (GPA). Half slowly lowered their prednisone to 5 mg per day, while the other half stopped completely. The goal was to see which approach better prevented disease flares over abo…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Phase: PHASE3 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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Could a tiny dose of an alcoholism drug ease vasculitis pain?
Symptom relief CompletedThis study tested whether a very low dose of naltrexone, a drug already approved for alcoholism, can improve physical health and quality of life in people with vasculitis (a group of rare diseases causing blood vessel inflammation). Sixty adults with different types of vasculitis…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated May 26, 2026 08:51 UTC
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Scientists probe immune cell secrets to improve vasculitis care
Knowledge-focused CompletedThis completed study looked at 93 people with a rare blood vessel inflammation disease called granulomatosis with polyangiitis (GPA). Researchers studied neutrophils, a type of immune cell, to understand why they become overactive and damage the body. The goal was to find new mar…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 26, 2026 08:33 UTC