GLIOMA, MALIGNANT
Clinical trials for GLIOMA, MALIGNANT explained in plain language.
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New drug aims to control brain cancer recurrence in early trial
Disease control Recruiting nowThis early-phase study tests the safety of an experimental drug called CUE-102 in 18 adults whose glioblastoma (a type of brain cancer) has returned after initial treatment. The drug is designed to help the immune system target cancer cells. The main goal is to find the safest do…
Matched conditions: GLIOMA, MALIGNANT
Phase: PHASE1 • Sponsor: David Reardon, MD • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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New drug targets deadly brain cancer in early trial
Disease control Recruiting nowThis study tests a new drug called LMP744 in 40 adults whose glioblastoma (a type of brain cancer) has come back after standard treatment. The drug is given through a vein for 5 days each month for up to a year. The goal is to see if it can shrink tumors or slow their growth.
Matched conditions: GLIOMA, MALIGNANT
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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Stem cells loaded with virus take on brain cancer in new trial
Disease control Recruiting nowThis early-stage trial tests whether giving multiple doses of a special stem cell treatment (NSC-CRAd-S-pk7) directly into the brain is safe and possible for people with newly diagnosed high-grade glioma. The stem cells are designed to deliver a virus that attacks cancer cells. P…
Matched conditions: GLIOMA, MALIGNANT
Phase: PHASE1 • Sponsor: Northwestern University • Aim: Disease control
Last updated May 26, 2026 08:31 UTC
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New targeted pill shows promise for Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new oral drug, TNG456, in people with advanced solid tumors that lack a gene called MTAP. The drug aims to slow or stop cancer growth by blocking a protein these tumors rely on. The trial has two parts: first finding the safest dose, then testing how well it wo…
Matched conditions: GLIOMA, MALIGNANT
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New imaging test aims to end guesswork in pediatric brain tumor care
Diagnosis Recruiting nowThis study is testing whether a special PET-MRI scan using 18F-fluciclovine can help doctors tell the difference between actual tumor growth and harmless changes that happen after treatment in children with high-grade glioma. About 30 children aged 1 to 21 with this type of brain…
Matched conditions: GLIOMA, MALIGNANT
Phase: EARLY_PHASE1 • Sponsor: Children's Hospital of Philadelphia • Aim: Diagnosis
Last updated May 20, 2026 11:54 UTC
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Brain tumor patients get a mental boost from Home-Based rehab
Symptom relief Recruiting nowThis study tests a remote cognitive rehabilitation program for people with slow-growing brain tumors (grade 2 or 3 glioma). Participants will use a digital program with human support to improve memory, attention, and thinking skills. The goal is to ease cognitive symptoms and imp…
Matched conditions: GLIOMA, MALIGNANT
Phase: NA • Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Symptom relief
Last updated May 26, 2026 08:32 UTC
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New drug targets brain tumors in short Pre-Surgery study
Knowledge-focused Recruiting nowThis study tests an oral drug called DSP-0390 in 20 people with IDH-mutant gliomas who are scheduled for brain tumor removal. Participants take the drug for about two weeks before surgery, and researchers measure how much drug reaches the tumor and blood. The goal is to see if th…
Matched conditions: GLIOMA, MALIGNANT
Phase: EARLY_PHASE1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 26, 2026 08:35 UTC
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New scan could help track Kids' brain tumors without extra needles
Knowledge-focused Recruiting nowThis study is testing whether a special PET-MRI scan using a tracer called 18F-Fluciclovine can better monitor low-grade gliomas (a type of brain tumor) in children and young adults. About 30 participants will get the scan before starting treatment, then again at 3 months and 1 y…
Matched conditions: GLIOMA, MALIGNANT
Phase: EARLY_PHASE1 • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC