GENITOURINARY CANCER

This study is testing whether a cancer drug called atezolizumab works better when given to people whose tumor DNA analysis suggests they might respond to it. It will enroll about 200 adults with various advanced, incurable solid tumors. Participants will receive the drug every th…

This early-stage study is testing whether two new immunotherapy drugs, M7824 and PDS01ADC, can help the body's immune system fight advanced bladder, kidney, and related cancers that have spread. Researchers want to see if adding a precise, high-dose radiation treatment (SBRT) mak…

This early-stage trial is testing a two-part personalized treatment for adults with advanced solid cancers that have spread and contain specific KRAS gene mutations. Doctors take a patient's own immune cells, genetically modify them in a lab to recognize and attack cancer cells w…

This study is testing whether a drug called riluzole can help prevent the memory and thinking problems often called 'chemo brain' in people receiving chemotherapy for various cancers. About 24 adult patients will be randomly assigned to receive either riluzole or a placebo pill w…

This study aims to understand how many opioid pain pills patients actually take after cancer surgery and what they do with leftover pills. Researchers will survey about 700 patients for 30 days after they leave the hospital to track their medication use and disposal habits. In th…

This study is testing a blood test that looks for tiny pieces of tumor DNA to see if it can detect cancer recurrence earlier than standard scans. It aims to enroll 100 adults, including people with various solid tumors and healthy volunteers. The goal is to gather information tha…

This study aims to understand the course of rare cancers in the urinary system (like bladder, kidney, and prostate cancers) by tracking patients over time. Researchers will collect medical information, blood, urine, and sometimes tumor samples from about 1,100 adults with these c…